致力于将循证医学范式与人工智能技术相结合，推动临床研究与医疗决策的科学化、精准化与智能化；具体涉及医学人工智能、流行病学、循证医学、健康数据科学、妇幼健康。
主要研究方向
研究方向一：循证医学与人工智能方法融合创新
致力于将循证医学与人工智能技术相融合，推动临床研究与医疗决策的科学化、精准化与智能化。开发疾病风险动态预测模型并评估风险分层干预临床效果，助力个体化临床决策，包括：利用时序深度学习模型，从纵向数据中捕捉疾病风险的动态演变规律；构建可解释的机器学习模型，识别干预效果异质性来源；基于AI仿真技术在复杂的真实世界数据中评估干预策略的长期效果与成本效益等；同时探索基于人工智能的证据合成方法，推动循证医学向动态、精准、可计算的方向演进。
研究方向二：妇幼健康与疾病防控研究
聚焦妇女与儿童全生命周期健康，重点围绕妊娠期并发症（如子痫前期、妊娠期糖尿病）、不良出生结局（如早产、低出生体重）以及儿童生长发育（如肥胖、神经发育迟缓、生殖发育等）开展系统研究。依托出生队列与临床数据库，整合多维度、多模态数据，揭示影响妇幼健康的关键环境、遗传与社会决定因素；构建疾病风险分层预测工具；在此基础上，设计与评估针对高危人群的早期干预策略，推动实现从“疾病治疗”到“风险防控”的关口前移，助力提升母婴健康水平与全人群生命质量。
科技项目及获奖情况
国家自然科学基金青年基金，负责人，在研，2024/01 - 2026/12
广东省基础与应用基础研究基金联合项目-面上基金，负责人，在研，2026/01 - 2028/12
中国博士后科学基金，负责人，结题，2023/08 - 2025/12
中国博士后特别资助项目，负责人，结题，2024/08 - 2025/12
代表性论文
•Ying Li#; Qi Feng#; Shiyu Wang; Bingyu Li; Bang Zheng; Nana Peng; Bingli Li; Yiwen Jiang; Di Liu; Zhirong Yang*; Feng Sha*; Jinling Tang; The association between urinary sodium and the risk of dementia: Evidence from a population-based cohort study, Journal of Affective Disorders, 2024, 362: 518-528
•Yuguo Deng; Lanyun Liu; Danxiu Lu; Qiulu Wu; Ying Li*; Jinying Yang*, Reference interval for twenty-four-hour urinary protein excretion in uncomplicated women with twin pregnancies, AJOG Global Reports, 2025, 6 (1): 100583
•Peng Wu, Fuxiao Li, Tengfei Lin, Qingping Yun, Ying Li, Shiyu Wang, Zhirong Yang*, Feng Sha, Jinling Tang*; Long-term risk of venous thromboembolism following hip or knee replacement surgery: a population-based matched cohort study, Research and Practice in Thrombosis and Haemostasis, 2025 Sep 30;9(7):103199.
•Ying Li#; Shunqing Xu; Yuanyuan Li; Bin Zhang; Wenqian Huo; Yingshuang Zhu; Yanjian Wan; Tongzhang Zheng; Aifen Zhou; Zhong Chen; Zheng Huang; Jie Hu; Wenxin Zhang; Xianliang Wang; Dan Ye; Wei Xia*; Association between urinary parabens and gestational diabetes mellitus across prepregnancy body mass index categories, Environmental Research, 2019, 170: 151-159
•Ying Li#; Yanqiu Zhou#; Zongwei Cai; Ruizhen Li; Pei Leng; Hongxiu Liu; Juan Liu; Gaga Mahai; Yuanyuan Li; Shunqing Xu; Wei Xia*; Associations of benzotriazoles and benzothiazoles with estrogens and androgens among pregnant women: A cohort study with repeated measurements, Science of The Total Environment, 2022, 838: 155998
•Yanqiu Zhou#; Ying Li#; Shunqing Xu; Jiaqiang Liao; Hongna Zhang; Jiufeng Li; Yanjun Hong; Wei Xia*; Zongwei Cai*; Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study, Journal of Hazardous Materials, 2020, 398: 122828
•Xiaoxia Lu#; Liqiong Zhang#; Hui Du#; Jingjing Zhang#; YuanYuan Li#;…; Ying Li; Chuansha Wu; Hongxiu Liu; Di Liu; Jianbo Shao; Xuehua Pen; Yonghong Yang; Zhisheng Liu; Yun Xiang; Furong Zhang; Rona M Silva; Kent E Pinkerton; Kunling Shen*; Han Xiao*; Shunqing Xu*; Gary W K Wong*; Chinese Pediatric Novel Coronavirus Study Team; SARS-CoV-2 Infection in Children, The New England Journal of Medicine, 2020, 382(17): 1663-1665
•Qing Guo#; Yi Tang; Ying Li; Ziyuan Xu; Di Zhang; Jiangtao Liu; Xin Wang; Wei Xia*; Shunqing Xu; Perinatal High-Salt Diet Induces Gut Microbiota Dysbiosis, Bile Acid Homeostasis Disbalance, and NAFLD in Weanling Mice Offspring, Nutrients, 2021, 13(7): 2135
•Di Liu#, Siyang Feng#, Feng Sha#, Yuxue Liao, …, Ying Li, Fengcai Zhu, Zhirong Yang*, Qiuying Lv*, Zijian Feng*, Jinling Tang; Inactivated SARS-CoV-2 Vaccine Booster Against Omicron Infection Among Quarantined Close Contacts, JAMA Network Open, 2023, 6(10): 0-e2339507
•Yitao Huo#; Yanjian Wan#; Ying Li; Liwen Lan; Silan Chen; Shunqing Xu; Chao Xiong*; Wei Xia*; Associations of pentachlorophenol exposure during pregnancy with maternal and infant reproductive hormones based on a birth cohort, Science of The Total Environment, 2024, 932: 172723
•Jiangtao Liu#; Tingting Yang; Ying Li; Shulan Li; Yuanyuan Li; Shunqing Xu; Wei Xia*; Associations of maternal exposure to 2,4-dichlorophenoxyacetic acid during early pregnancy with steroid hormones among one-month-old infants, Science of the Total Environment, 2024, 912: 0-169414
•Ling Yu#; Jiangtao Liu#; Ying Li; Shulan Li; Shuting Cao; Fasheng Li; Yuanyuan Li; Hongxiu Liu; Zhenyu He*; Shunqing Xu*; Wei Xia*; Associations between prenatal exposure to metal mixtures and infant reproductive hormones during mini-puberty, Science of The Total Environment, 2024, 955: 177192
•Yanqiu Zhou#; Jingyu Qu#; Wenyu Liu; Jiaqiang Liao; Ying Li; Hongzhi Zhao; Jiufeng Li; Hangbiao Jin; Hongxiu Liu; Jing Fang; Xiaojie Sun; Yangqian Jiang; Shunqing Xu; Yuanyuan Li; Yanjun Hong; Wei Xia*; Zongwei Cai*; Early pregnancy exposure to benzotriazoles and benzothiazoles in relation to gestational diabetes mellitus: A prospective cohort study, Environment International, 2020, 135: 105360
•Gaga Mahai#; Yanjian Wan; Aizhen Wang; Xi Qian; Juxiao Li; Ying Li; Wenxin Zhang; Zhenyu He; Yuanyuan Li; Wei Xia*; Shunqing Xu*; Exposure to multiple neonicotinoid insecticides, oxidative stress, and gestational diabetes mellitus: Association and potential mediation analyses, Environment International, 2023, 179: 08173
•Gaga Mahai#; Yanjian Wan#; Wei Xia*; Aizhen Wang; Xi Qian; Ying Li; Zhenyu He; Yuanyuan Li; Shunqing Xu; Exposure assessment of neonicotinoid insecticides and their metabolites in Chinese women during pregnancy: A longitudinal study, Science of The Total Environment, 2022, 818: 151806
•Hongling Zhang#; Juxiao Li#; Yuanyuan Li*; Fenghua Xu*; Meng Wang; Xiaofang Lin; Ying Li; Chenhui Yang; Zhongqiang Cao; Wei Xia; Shunqing Xu; Sex-specific associations of early postnatal blood copper levels with neurodevelopment at 2 years of age, Journal of Trace Elements in Medicine and Biology, 2022, 74: 127072
•Qi Liu#; Wei Xia*; Xin Xiong; Juxiao Li; Ying Li; Shunqing Xu; Yuanyuan Li; Associations of Gestational Diabetes Mellitus and Excessive Gestational Weight Gain with Offspring Obesity Risk, Current Medical Science, 2022, 42(3): 520-529
专利
医学数据链路集成与分析装置、方法、设备以及存储介质，发明专利，2025，第二作者（2/5）
基于智能治理的诊疗数据仓库构建方法及系统，发明专利，2025，第四作者（4/5）
