(国际影响力)
2020-至今:编委,《合成生物学》编委会
2019-至今:理事,粤港澳肠道微生态学术联盟
2019-至今:委员,中国医药生物技术协会合成生物技术分会
2018-至今:委员,中国生物工程学会合成生物学专业委员会
审稿人:Nature Chemical Biology, PNAS, Ecology Letters, Genetics, PLOS Computational Biology, Scientific Reports,微生物学通报等学术期刊
(所获荣誉)
入选2019年《麻省理工科技评论》中国区“35岁以下科技创新35人”
(科研成果)
项目
国家自然科学基金面上项目,基于时序数据预测微生物群落的生态稳定性,2020.01-2023.12,58万,在研,项目负责人,项目编号:31971513
国家重点研发计划“合成生物学”重点专项青年项目,治疗炎症性肠病的合成肠道菌群的构建及应用,2020年01月 至2024年12月,441万,在研,项目负责人,项目编号:2019YFA09006700)
国家自然科学基金国际(地区)合作与交流项目,植物代谢产物对根际微生物生态网络的调控,2020.10-2023.09,200万,项目编号:32061143023
深圳市医学研究专项资金,肠黏膜屏障的空间微生物组学研究,2024年01月01日-2026年12月31日,300万,B2302036
Lu Wu#, Xu-Wen Wang#, Zining Tao, Tong Wang, Wenlong Zuo, Yu Zeng, Yang-Yu Liu# , Lei Dai* . Data-driven prediction of colonization outcomes for complex microbial communities.Nature Communications,2024.3.16.15(1):2406.
Shen J, Zhang J, Mo L, Li Y, Li Y, Li C, Kuang X, Tao Z, Qu Z, Wu L, Chen J, Liu S, Zeng L, He Z, Chen Z, Deng Y, Zhang T, Li B, Dai L*, Ma Y*.Large-scale phage cultivation for commensal human gut bacteria. Cell Host Microbe,2023,31(4):665-677.
Chunhua Zhou, Ying Wang, Cun Li, Zhiyong Xie*, Lei Dai*.Amelioration of colitis by a gut bacterial consortium producing anti-inflammatory secondary bile acids. Microbiology Spectrum.2023,11(2):e0333022.
Zhaohui Cao#, Wenlong Zuo#, Lanxiang Wang, Junyu Chen, Zepeng Qu, Fan Jin, Lei Dai*.Spatial profiling of microbial communities by sequential FISH with error-robust encoding Nature Communications, 2023, 14(1):1477.
Lanxiang Wang*, Moxian Chen*, Pui-Ying Lam, Francisco Dini-Andreote, Lei Dai#, Zhong Wei#.Multifaceted roles of flavonoids mediating plant-microbe interactions.Microbiome, 2022,10(1):233.
Han Hu#, Yuxiang Tan#, Chenhao Li#, Junyu Chen, Yan Kou, Zhenjiang Zech Xu, Yang-Yu Liu, Yan Tan*, Lei Dai*.StrainPanDA: linked reconstruction of strain composition and gene contents from metagenomic data.iMeta,2022,1:e41.
Hongbin Liu#, Chen Liao#, Lu Wu, Jinhui Tang, Junyu Chen, Chaobi Lei, Linggang Zheng, Chenhong Zhang, Yang-Yu Liu, Joao Xavier, Lei Dai*.Ecological dynamics of the gut microbiome in response to dietary fiber. ISME Journal,2022, 16(8):2040-2055.
Linggang Zheng#, Yang Tan#*, Yucan Hu, Juntao Shen, Zepeng Qu, Xianbo Chen, Chun Loong Ho, Elaine Lai-Han Leung, Wei Zhao, Lei Dai*. CRISPR/Cas-based genome editing for human gut commensal Bacteroides species.ACS Synthetic Biology,2022, 11(1):464-472.
Ying Wang*, Jinhui Tang*, Qingqing Lv, Yuxiang Tan, Xiaoxiao Dong, Hongbin Liu, Nannan Zhao, Zhen He, Yan Kou, Yan Tan, Xin-an Liu, Liping Wang, Yang-Yu Liu, Lei Dai#. Establishment and resilience of transplanted gut microbiota in aged mice.iScience,202225(1):103654.
Lei Dai#,Yushen Du#, Hangfei Qi,Christian D. Huber,Dongdong Chen, Tian-Hao Zhang, Nicholas C. Wu,Ergang Wang,James O. Lloyd-Smith, Ren Sun*.Quantifying the Evolutionary Constraints and Potential of Hepatitis C Virus NS5A Protein.mSystems,2021,6(2):e01111-20.
YanKou,XiaominXu,ZhengnongZhu,LeiDai*,YanTan*.Microbe-set enrichment analysis facilitates functional interpretation of microbiome profiling data.ScientificReports,2020,10(1):21466.
Tian-hao Zhang#, Lei Dai#*, John P. Barton, Yushen Du, Yuxiang Tan,Wenwen Pang, Arup K. Chakraborty, James O. Lloyd-Smith, Ren Sun*.Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease. PLoS Genetics,2020,16(10):e1009009.
YangTan,JuntaoShen,TongSi,ChunLoongHo,YinqingLi,LeiDai*.Engineered Live Biotherapeutics: Progress and Challenges.BiotechnologyJournal,2020, 15(10):e2000155.