1.Duojia Pan, Jian-Dong Huang, and Albert J. Courey (October, 1991). Functional Analysis of the Drosophila Twist Promoter Reveals a Dorsal-Binding Ventral Activator Region. Genes and Development, V5 (10): 1892-1901. [Abstract] [PDF] (IF= 16.385, (2004))
2.Jian-Dong Huang, Deborah H. Schwyter, Jill M. Shirokawa, and Albert J. Courey (April, 1993). The Interplay Between Multiple Enhancer and Silencer Elements Defines the Pattern of Decapentaplegic Expression. Genes & Development, V7 (4): 694-704. [Abstract] [PDF] (IF= 16.385, (2004))
3.Deborah H. Schwyter, Jian-Dong Huang, Todd Dubnicoff, and Albert J. Courey (July, 1995). The Decapentaplegic Core Promoter Region Plays an Integral Role in the Spatial Control of Transcription. Molecular and Cellular Biology. V15 (7): 3960-3968. [Abstract] [PDF] (IF= 7.822, (2004))
4.Gwo-Jen Liaw, Karen M. Rudolph, Jian-Dong Huang, Todd Dubnicoff, Albert J. Courey, and Judith A. Lengyel (December, 1995). The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes & Development, V9 (24): 3163-76. [Abstract] [PDF] (IF= 16.385, (2004))
5.Jian-Dong Huang, Todd Dubnicoff, Gwo-Jen Liaw, Yijian Bai, Scott A. Valentine, Jill M. Shirokawa, Judith A. Lengyel, and Albert J. Courey (December, 1995). Binding Sites For Transcription Factor NTF-1/Elf-1 Contribute To The Ventral Repression Of Decapentaplegic. Genes & Development, V9 (24): 3177-89. [Abstract] [PDF] (IF= 16.385, (2004))
6.Jian-Dong Huang, M. Jamie T. V. Cope, Valerie Mermall, Marjorie C. Strobel, John Kendrick-Jones, Liane B. Russell, Mark S. Mooseker, Neal G. Copeland, and Nancy A. Jenkins (April, 1998). Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Head Region Mutations. Genetics, V148 (4): 1951-1961. [Abstract] [Full text] [PDF] (IF= 4.289, (2005))
7.Jian-Dong Huang,Valerie Mermall, Marjorie C. Strobel, Liane B. Russell, Mark S. Mooseker, Neal G. Copeland and Nancy A. Jenkins (April, 1998). Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Tail Region Mutations. Genetics, V148 (4): 1963-1972. [Abstract] [Full text] [PDF] (IF= 4.289, (2005))
8.Jian-Dong Huang, Scott T. Brady, Bruce W. Richards, David Stenoien, James H. Resau, Neal G. Copeland & Nancy A. Jenkins (January, 1999). Direct interaction of microtubule- and actin-based transport motors. Nature, V397: 267-270 [Abstract] [Full text] [PDF] (IF= 32.182, (2004))
9.Julie M. Jones, Jian-Dong Huang, Valerie Mermall, Bruce A. Hamilton, Mark S. Mooseker, Andrew Escayg, Neal G. Copeland, Nancy A. Jenkins and Miriam H. Meisler, (March, 2000). The mouse neurological mutant flailer results from exon shuffling between Gnb5 and Myo5a to generate a novel hybrid gene. Human Molecular Genetics, V9 (5): 821-828 [Abstract] [Full text] [PDF] (IF=7.801, (2004))
10.Josephine Sui-Yan Au and Jian-Dong Huang (October, 2002). A tissue specific exon of Myosin Va is responsible for selective cargo binding in melanocytes. Cell Motility and the Cytoskeleton, V53 (2): 89-102 [Abstract] [Full text] [PDF] (IF=3.068, (2004))
11.Xin-Mei Zhang and Jian-Dong Huang (August, 2003). Combination of overlapping bacterial artificial chromosomes by a two-step recombinogenic engineering method. Nucleic Acids Research, V31 (15): e81 [Abstract] [Full text] [PDF] (IF=7.552, (2005))
12.Julian A. Tanner, Rory M. Watt, Yu-Bo Chai, Lin-Yu Lu, Marie C. Lin, J. S. Malik Peiris, Leo L. M. Poon, Hsiang-Fu Kung, and Jian-Dong Huang (October, 2003). The Severe Acute Respiratory Syndrome (SARS) Coronavirus NTPase/Helicase Belongs to a Distinct Class of 5’ to 3’ Viral Helicases. Journal of Biological Chemistry, V278 (41): 39578-39582. First Published on August 13, 2003 as Accelerated Publications; doi:10.1074/jbc.C300328200 [Abstract] [Full Text] [PDF] Supplemental Data (IF=6.355, (2004))
13.Liu Yang (楊柳), Zhoujing Luo (羅卓荊), Qiang Ji (頡強), Xiaobing Jin (靳小兵), Danny Chan, Wing-Sum Hui, Jian-Dong Huang, Kenneth M.C. Cheung, Kathryn S.E.Cheah (October, 2003). Culture of chondrocytes of hereditary multiple exostosis in vitro. Chinese Journalof Clinical Rehabilitation, V7 (26): 3590-3591
14.Xin-tian Li, Nina Costantino, Lin-yu Lu, De-pei Liu, Rory M. Watt, Kathryn S. E. Cheah, Donald L. Court and Jian-Dong Huang (November, 2003). Identification of factors influencing strand bias in oligonucleotide–mediated recombination in E. coli. Nucleic Acids Research, V31 (22): 6674-6687. [Abstract] [Full Text] (IF=7.552, (2005))
(Faculty of 1000: evaluations for Li XT et al Nucleic Acids Res 2003 Nov 15 31 (22) :6674-6687 http://www.f1000biology.com/article/14602928/evaluation)
15.Xin-Mei Zhang, Alam Hoi-Lam Ng, Julian A. Tanner, Wu-Tian Wu, Neal G. Copeland, Nancy A. Jenkins, and Jian-Dong Huang (September, 2004). Highly Restricted Expression of Cre Recombinase in Cerebellar Purkinje Cells. genesis: The Journal of Genetics and Development (formerly Developmental Genetics), V40: 45-51. [Abstract] [PDF] (IF=2.491, (2004))
16.Richard Y. Kao, Wayne H.W. Tsui, Terri S.W. Lee, Julian A. Tanner, Rory M. Watt, Jian-Dong Huang, Lihong Hu, Guanhua Chen, Zhiwei Chen, Linqi Zhang, Tian He, Kwok-Hung Chan, Herman Tse, Amanda P.C. To, Louisa W.Y. Ng, Bonnie C.W. Wong, Hoi-Wah Tsoi, Dan Yang, David D. Ho, and Kwok-Yung Yuen (September, 2004). Identification of Novel Small-Molecule Inhibitors of Severe Acute Respiratory Syndrome-Associated Coronavirus by Chemical Genetics. Chemistry & Biology, V11 (9): 1293-1299. [Abstract] [Full Text] [PDF] (IF=5.725, (2004))
17.T. Norene O’Sullivan, Xufeng S. Wu, Rivka A. Rachel, Jian-Dong Huang, Deborah A. Swing, Lydia E. Matesic, John A. Hammer III, Neal G. Copeland, and Nancy A. Jenkins (November, 2004) dsu Functions in a MYO5A-Independent Pathway to Suppress the Coat Color of Dilute Mice. Proceedings of the National Academy of Sciences, V101 (48): 16831-16836. [Abstract] [Full Text] [PDF] (IF= 10.452, (2004))
18.Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Stefano Chiellini, Luisa Bracci, Xiyun Yan, Bojian Zheng, Jian-Dong Huang, Ming-Liang He, Huai-Dong Song, Pei Hao, Guoping Zhao, Neri Niccolai (December, 2004) Prediction of Quaternary Assembly of SARS Coronavirus Peplomer. Biochemical and Biophysical Research Communications, V325 (4): 1210-1214. [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
19.Xue-Song Wu, Li Xin, Wen-Xuan Yin, Xi-Ying Shang, Lu Lu, Rory M. Watt, Kathryn S. E. Cheah, Jian-Dong Huang, De-Pei Liu, and Chih-Chuan Liang (February, 2005). Increased Efficiency of Oligonucleotide-Mediated Gene Repair Through Slowing Replication Fork Progression. Proceedings of the National Academy of Sciences, V102(7): 2508–2513 [Abstract] [Full Text] [PDF] (IF= 10.452, (2004))
20.Julian A. Tanner, Bo-Jian Zheng, Jie Zhou, Rory M. Watt, Jie-Qing Jiang, Kin-Ling Wong, Yong-Ping Lin, Lin-Yu Lu, Ming-Liang He, Hsiang-Fu Kung, Andreas J. Kesel, and Jian-Dong Huang (March, 2005). The Adamantane-Derived Bananins are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus, Chemistry & Biology, V12: 303-311 [Summary] [Full Text] [PDF] [Supplemental Data] (IF=5.725, (2004))
21.Queenie N. Y. Wong, Vivian C. W. Ng, Marie C. M. Lin, Hsiang-fu Kung, Danny Chan and Jian-Dong Huang (March, 2005). Efficient and Seamless DNA Recombineering using a Thymidylate Synthase A Selection System in Escherichia coli, Nucleic Acids Research, V33(6), e59 [Abstract] [Full Text] [PDF] (IF=7.552, (2005))
22.Matthew J. Tyska, Andrew T. Mackey, Jian-Dong Huang, Neil G. Copeland, Nancy A. Jenkins, and Mark S. Mooseker (May, 2005). Myosin-1a Is Critical for Normal Brush Border Structure and Composition, Molecular Biology of the Cell, V16(5): 2443-2457 [Abstract] [Full Text] [PDF] (IF= 7.517, (2004))
23.Bo-Jian Zheng*, Yi Guan, Ming-Liang He, Hongzhe Sun, Lanying Du, Ying Zheng, Kin-Ling Wong, Honglin Chen, Ying Chen, Linyu Lu, Julian A Tanner, Rory M Watt, Neri Niccolai, Andrea Bernini, Ottavia Spiga, Patrick CY Woo, Hsiang-fu Kung, Kwok-Yung Yuen and Jian-Dong Huang* (2005). Synthetic Peptides Outside the Spike Protein Heptad Repeat Regions as Potent Inhibitors of SARS-Associated Coronavirus, Antiviral Therapy, V10(3): 393-403 (* co-corresponding author) [Abstract] [PDF] (IF= 6.036, (2004))
24.Baohua Liu, Jianming Wang, Kui Ming Chan, Wai Mui Tjia, Wen Deng, Xinyuan Guan, Jian-Dong Huang, Kai Man Li, Pui Yin Chau, David J Chen, Duanqing Pei, Alberto M Pendas, Juan Cadiñanos, Carlos López-Otín, Hung Fat Tse, Chris Hutchison, Junjie Chen, Yihai Cao, Kathryn S E Cheah, Karl Tryggvason & Zhongjun Zhou (July, 2005). Genomic Instability in Laminopathy-based Premature Aging, Nature Medicine, V11(7): 780-785. [Abstract] [Full Text] [PDF] (IF= 31.223, (2004))
(Faculty of 1000 Biology: evaluations for Liu B et al Nat Med 2005 Jul 11 (7) :780-5 http://www.f1000biology.com/article/id/1026680/evaluation)
25.Wen-Xuan Yin, Xue-Song Wu, Guang Liu, Zhu-Hong Li, Rory M. Watt, Jian-Dong Huang, De-Pei Liu, Chih-Chuan Liang (September, 2005). Targeted correction of a chromosomal point mutation by modified single-stranded oligonucleotides in a GFP recovery system. Biochemical and Biophysical Research Communications, V334(4):1032-1041, [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
26.Xin-Mei Zhang, Bai-Yu Chen, Alam Hoi-Lam Ng, Julian A. Tanner, David Tay, Kwok-Fai So, Rivka A. Rachel, Neal G. Copeland, Nancy A. Jenkins, and Jian-Dong Huang (October, 2005) Transgenic Mice Expressing Cre-Recombinase Specifically in Retinal Rod Bipolar Neurons. Investigative Ophthalmology & Visual Science (IOVS) V46: 3515-3520, [Abstract] [Full Text] [PDF] (IF= 3.643, (2005))
27.Ruiguang Ge, Rory M. Watt, Xuesong Sun, Julian A. Tanner, Qing-Yu He, Jian-Dong Huang* and Hongzhe Sun* (January, 2006). Expression and Characterization of the Histidine-rich Protein, Hpn: Potential for Nickel Storage in Helicobacter pylori. Biochemical Journal, V393(1): 285-293 (* co-corresponding author) [Abstract] [Full Text] [PDF] (IF= 4.278, (2004))
(Faculty of 1000 Biology: evaluations for Ge R et al Biochem J 2006 Jan 1 393 (Pt 1) :285-93 http://www.f1000biology.com/article/id/1033680/evaluation)
28.Andrea Bernini, Ottavia Spiga, Vincenzo Venditti, Filippo Prischi, Luisa Bracci, Jian-Dong Huang, Julian A. Tanner, Neri Niccolai (2006 May 19, Epub 2006 Mar 23) Tertiary Structure Prediction of SARS coronavirus helicase. Biochemical and Biophysical Research Communications, V343(4):1101-1104. [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
29.Ying Peng, Pai-Hao Yang, Julian A. Tanner, Jian-Dong Huang, Ming Li, Henry F. Lee, Ren-He Xu, Hsiang-Fu Kung, Marie C.M. Lin (2006 May 26, Epub 2006 Mar 24) Cold-Inducible RNA Binding Protein is Required for the Expression of Adhesion Molecules and Embryonic Cell Movement in Xenopus Laevi. Biochemical and Biophysical Research Communications, V344(1): 416-424. [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
30.Ming-Liang He, Bo-jian Zheng, Ying Chen, Kin-Ling Wong, Jian-Dong Huang, Marie C. Lin, Ying Peng, Kwok Y. Yuen, Joseph J.Y. Sung, Hsiang-fu Kung (2006 May 1, Epub 2006 Mar 30) Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS associated coronavirus. FEBS Letters, V580(10): 2414-20 [Abstract] [Full Text] [PDF] (IF=3.415, (2005))
31.Lanying Du, Yuxian He, Yijia Wang, Haojie Zhang, Selene Ma, Charlotte K.L. Wong, Sharon H.W. Wu, Fai Ng, Jian-Dong Huang, Kwok-Yung Yuen, Shibo Jiang, Yusen Zhou, Bo-Jian Zheng (September 15, 2006, Epub June 20, 2006) Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines. Virology V353(1):6-16 [Abstract] [Full Text] [PDF] (IF=3.080, (2005))
32.Ruiguang Ge, Yi Zhang, Xuesong Sun, Rory M. Watt, Qing-Yu He, Jian-Dong Huang, Dean E. Wilcox, and Hongzhe Sun (September 6, 2006). Thermodynamic and Kinetic Aspects of Metal Binding to the Histidine-rich Protein, Hpn. Journal of the American Chemical Society; (Communication), V128(35):11330-1 [Abstract] Full Text HTML | Hi-Res PDF | PDF w/ Links (IF= 7.419, (2005))
33.Zai Wang, Zhong-Jun Zhou, De-Pei Liu, Jian-Dong Huang (November 24, 2006, Available online 26 September 2006). Single-Stranded Oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair. Biochemical and Biophysical Research Communications, V350(3): 568–573. [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
34.Michael S. Y. Huen, Xin-tian Li, Lin-Yu Lu, Rory M. Watt, De-Pei Liu and Jian-Dong Huang (2006 December 1, Published online 2006 November 6). The involvement of replication in single stranded oligonucleotide-mediated gene repair, Nucleic Acids Research V34(21):6183–6194; doi:10.1093/nar/gkl852 [Abstract] [FREE Full Text] [Print PDF][Screen PDF] (IF=7.552, (2005))
35.Michael S.Y. Huen, Lin-Yu Lu, De-Pei Liu, Jian-Dong Huang (February 2, 2007, Available online 8 December 2006) Active transcription promotes single-stranded oligonucleotide mediated gene repair, Biochemical and Biophysical Research Communications, V353(1):33-39. [Abstract] [Full Text] [PDF] (IF= 3.000, (2005))
36.Rory M. Watt, Jing Wang, Meikid Leong, Hsiang-fu Kung, Kathryn S.E. Cheah, Depei Liu, Antoine Danchin and Jian-Dong Huang (2007, Published online January 31, 2007). Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. Nucleic Acids Research V35(6):e37 doi:10.1093/nar/gkl1158 [Abstract] [Full Text] [Print PDF] [Screen PDF] (IF=7.552, (2005)) (Faculty of 1000 Biology: evaluations for Watt RM et al Nucleic Acids Res 2007 35 (6) :e37 http://www.f1000biology.com/article/id/1088949/evaluation)
37.Ruiguang Ge, Xuesong Sun, Qing Gu, Rory M. Watt, Julian A. Tanner, Benjamin Chun Yu Wong, Harry Huaxiang Xia, Jian-Dong Huang, Qing-Yu He, and Hongzhe Sun (August 2007, Available online May 15, 2007). A Proteomic Approach for Identification of Bismuth-binding Proteins in Helicobacter pylori. Journal of Biological Inorganic Chemistry, V12(6):831-842 [Abstract] [Full Text] [PDF] (IF= 3.303, (2006)) doi: 10.1007/s00775-007-0237-7
38.Nan Yang, Julian A. Tanner, Bo-Jian Zheng, Rory M. Watt, Ming-Liang He, Lin-Yu Lu, Jie-Qing Jiang, Ka-To Shum, Yong-Ping Lin, Kin-Ling Wong, Marie C. M. Lin, Hsiang-Fu Kung, Hongzhe Sun,* and Jian-Dong Huang* (2007, Published Online: 23 Jul 2007). Bismuth Complexes as Inhibitors of the SARS Coronavirus, Angewandte Chemie-International Edition, V46:6464-6468 [Abstract] [Full Text] [PDF] (* co-corresponding author) DOI: 10.1002/anie.200701021 (IF= 13.455, (2011))
39.Nan Yang, Julian A. Tanner, Zai Wang, Jian-Dong Huang, Bo-Jian Zheng, Nianyong Zhu and Hongzhe Sun (November 14, 2007, First published on the web 16th August 2007). Inhibition of SARS coronavirus helicase by bismuth complexes, Chemical Communications (Camb). (42):4413-4415. [Abstract] [Full Text] [PDF] (IF= 4.521, (2006)) DOI: 10.1039/b709515e
40.Xiaoping An., Jun Lu., Jian-Dong Huang*, Baozhong Zhang, Dabin Liu, Xin Zhang, Jinhui Chen, Yusen Zhou, Yigang Tong* (2007, published online November 14, 2007) Rapid assembly of multiple-exon cDNA directly from genomic DNA. PLoS ONE V2(11), e1179 [Abstract] [Full Text] [PDF] (* co-corresponding author) (IF= 4.411, (2010))
41.Chen-Li Liu, Li-Xia Xie, Min Li*, Siva Sundara Kumar Durairajan, Shinya Goto, Jian-Dong Huang* (published online December 19, 2007) Salvianolic Acid B Inhibits Hydrogen Peroxide-Induced Endothelial Cell Apoptosis through Regulating PI3K/Akt Signaling. PLoS ONE 2(12): e1321. doi:10.1371/journal.pone.0001321 (* co-corresponding author) [Abstract] [Full Text] [PDF] (IF= 4.411, (2010))
42.Siva Sundara Kumar Durairajan, Qiuju Yuan, Lixia Xie, Wing-Sai Chan, Wan-Fung Kum, Irene Koo, Chenli Liu, Youqiang Song, Jian-Dong Huang *, William L. Klein, Min Li * (2008, Available online 16 September 2007) Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty. Neurochemistry International, V52:741-750 [Abstract] [Full Text] [PDF] (* co-corresponding author) (IF=3.159, (2006)) doi:10.1016/j.neuint.2007.09.006
43.Lin-Yu Lu, Michael S.Y. Huen, Andrew Chi-Pang Tai, De-pei Liu, Kathryn S.E. Cheah, and Jian-Dong Huang (February 2008) Highly efficient deletion method for the engineering of plasmid DNA with single-stranded oligonucleotides. BioTechniques, V44(2): 217-224 (IF= 2.550, (2010))
44.Zai Wang, Zhong-Jun Zhou, De-Pei Liu, and Jian-Dong Huang (2008) Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells. Oligonucleotides, V 18(1):21-32 [Abstract] [PDF] (Journal renamed as Nucleic Acid Therapeutics) (IF= 2.808, (2006))
45.Zhi Li, Hong Yao, Yan Ma, Qingming Dong, Yangchao Chen, Ying Peng, Bo-jian Zheng, Jian-Dong Huang, Chu-yan Chan, Marie C. Lin, Joseph J. Sung, Kwok Yung Yuen, Hsiang-fu Kung, Ming-Liang He (March 31, 2008) Inhibition of HBV gene expression and replication by stably expressed interferon-α1 via adeno-associated viral vectors. Journal of Gene Medicine, V10(6):619-627. [Abstract] [Full Text] [PDF] (IF= 3.916)
46.Jian-Dong Huang, Bojian Zheng, and Hongzhe Sun (August, 2008) Helicases as antiviral targets. Hong Kong Medical Journal, V14(4) Supplement 4:36-38
47.Che-Man Chan, Patrick C. Y. Woo, Susanna K. P. Lau, Herman Tse, Hong-Lin Chen, Feng Li, Bo-Jian Zheng, Ling Chen, Jian-Dong Huang, and Kwok-Yung Yuen. (December, 2008, Epub ahead of print October 10, 2008) Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection. Experimental Biology And Medicine V233(12):1527-36 [Abstract] [Full Text] [PDF] (IF= 2.954, (2010))
48.Zhou, J., Smith, D.K., Lu, L., Poon, V.K.M., Ng, Fai., Chen, D.Q., Huang, J.D., Yuen, K.Y., Cao, K.Y., and Zheng, B.J. (January 2009, Epub August 28, 2008) A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic Hepatitis B Virus infection. Journal of Viral Hepatitis, V16(1):45-52. [Abstract] [Full Text] [PDF] (IF= 3.502, (2010))
49.Che Man Chan, Susanna K. P. Lau, Patrick C. Y. Woo, Herman Tse, Bo-Jian Zheng, Ling Chen, Jian-Dong Huang, and Kwok-Yung Yuen (January 2009, Epub ahead of print November 5, 2008) Identification of Major Histocompatibility Antigen Class I C as an attachment factor that facilitates Coronavirus HKU1 Spike-mediated infection. Journal of Virology V83(2):1026-1035 [Abstract] [Full Text] [PDF] (IF= 5.332)
50.Patrick C. Y. Woo, Susanna K. P. Lau, Herman Tse, Jade L. L. Teng, Shirly O. T. Curreem, Alan K. L. Tsang, Rachel Y. Y. Fan, Gilman K. M. Wong, Yi Huang, Nicholas J. Loman, Lori A. S. Snyder, James J. Cai, Jian-Dong Huang, William Mak, Mark J. Pallen, Si Lok, and Kwok-Yung Yuen (March 2009, Epub March 13, 2009) The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats. PLoS Genetics. V5(3):e1000416 [Abstract] [Full Text] [PDF] (IF= 9.543, (2010))
51.Ye Jin, Rory M. Watt, Antoine Danchin and Jian-Dong Huang (April 2009, Epub April 20, 2009) Small noncoding RNA GcvB is a novel regulator of acid resistance in Escherichia coli. BMC Genomics V10:165 [Abstract] [Full Text] [PDF] (IF= 4.206, (2010)). doi:10.1186/1471-2164-10-165
52.Hong-Yan Sui, Guang-Yu Zhao, Jian-Dong Huang, Dong-Yan Jin, Kwok-Yung Yuen, Bo-Jian Zheng. (May 22, 2009) Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza A virus replication. PLoS ONE V4(5), e5671, [Abstract] [Full Text] [PDF] (IF= 4.411, (2010))
53.Chan, C.M., Tse, H., Wong, S.S., Woo, P.C., Lau, S.K., Chen, .L, Zheng, B.J., Huang, J.D., and Yuen, K.Y. (May 2009, Epub ahead of print March 31, 2009) Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. Journal of Clinical Virology V45(1):54-60, [Abstract] [Full Text] [PDF] (IF= 3.468)
54.Jie Zhou*, Jian-Dong Huang*, Vincent K.M. Poon, Ding-Qiang Chen, Chris C.S. Chan, Fai Ng, Xin-Yuan Guan, Rory M. Watt, Liwei Lu, Kwok-Yung Yuen, Bo-Jian Zheng. (2009, Epub ahead of print May 3, 2009) Functional dissection of an IFN-α/β receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection. Journal of Hepatology V51(2):322-332 (*Equal contribution) [Abstract] [Full Text] [PDF]. (IF= 9.264, (2011))
55.Jie Zhou & Ding-Qiang Chen, Vincent K. M. Poon, Yong Zeng, Fai Ng, Liwei Lu, Jian-Dong Huang, Kwok-Yung Yuen & Bo-Jian Zheng. (June 2009, Epub ahead of print June 2, 2009) A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection. Immunogenetics V61(6):423-430, [Abstract] [Full Text] [PDF] (IF= 2.741) DOI 10.1007/s00251-009-0377-8
56.Mingliang He, Bojian Zheng, Ying Chen, Wong, K.L., Jian-Dong Huang, Marie M.C. Lin, Kwok-Yung Yuen, Joseph J. Sung, and Hsing fu Kung. (June 2009) Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication. Hong Kong Medical Journal V15(3) Supplement 4:28-31, [PDF]
57.Chenli Liu, Zai Wang, Michael S.Y. Huen, Lin-Yu Lu, De-Pei Liu, and Jian-Dong Huang (2009, Epub ahead of print August 5, 2009) Cell death caused by single-stranded oligodeoxynucleotides mediated targeted genomic sequence modification. Oligonucleotides (Journal renamed as Nucleic Acid Therapeutics), V19(3):281-286 [Abstract] [PDF] (IF= 2.000, (2008))
58.Muhan Chen, Jian-Dong Huang, Liang Hu, Bo-jian Zheng, Leilei Chen, Sze Lan Tsang, Xin-yuan Guan (August 24, 2009) Transgenic CHD1L expression in mouse induces spontaneous tumors. PLoS One V4(8):e6727, [Abstract] [Full Text] [PDF] (IF= 4.411, (2010))
59.Ye Jin, Rory M. Watt, Antoine Danchin, and Jian-Dong Huang (October 16, 2009, Epub August 25, 2009) Use of a riboswitch-controlled conditional hypomorphic mutation to uncover a role for the essential CsrA gene in bacterial autoaggregation. Journal of Biological Chemistry, V284(42):28738-28745, [Abstract] [Full Text] [PDF] (IF=5.520, (2008))
60.Jian-Dong Huang, Hongzhe Sun, Julian A. Tanner, and Rory M. Watt (October, 2009) Determine the functions of the putative metal-binding domain of SARS-CoV helicase. Hong Kong Medical Journal, V15(5) Supplement 6:15-16, [PDF]
61.Ding-Qiang Chen, Yong Zeng, Jie Zhou, Ling Yang, Shibo Jiang, Jian-Dong Huang, Liwei Lu, and Bo-Jian Zheng (2010) Association of candidate susceptible loci with chronic hepatitis B virus infection in Chinese population. Journal of Medical Virology V82:371–378, [Abstract] [PDF] (IF= 2.895 (2010))
62.Richard Y Kao, Dan Yang, Lai-Shan Lau, Wayne H W Tsui, Lihong Hu, Jun Dai, Mei-Po Chan, Che-Man Chan, Pui Wang, Bo-Jian Zheng, Jian Sun, Jian-Dong Huang, Jason Madar, Guanhua Chen, Honglin Chen, Yi Guan & Kwok-Yung Yuen (2010) Identification of influenza A nucleoprotein as an antiviral target. Nature Biotechnology V28, P600–605, [Abstract] [Full Text] [PDF] (IF= 31.085 (2010))
63.Li Xia Xie, Siva Sundara Kumar Durairajan, Jia Hong Lu, Chen Li Liu, Wan Fung Kum, Yan Wang, Irene Koo, Wei Kang Wu, Dong Han, Fulong Lao, Jian-Dong Huang and Min Li. (2010) The effect of salvianolic acid B combined with laminar shear stress on TNF-a-stimulated adhesion molecule expression in human aortic endothelial cells. Clinical Hemorheology and Microcirculation, V44, P245–258 [Abstract] [Full Text] [PDF] (IF= 2.838, (2010))
64.Liu Yang, Wing Sum Hui, Wilson C. W. Chan, Vivian C. W. Ng, Teresa H. Y. Yam, Helen C. M. Leung, Jian-Dong Huang, Daisy K. Y. Shum, Qiang Jie, Kenneth M. C. Cheung, Kathryn S. E. Cheah, Zhoujing Luo, Danny Chan (November, 2010, Article first published online: August 4, 2010) A splice site mutation leads to haploinsufficiency of EXT2 mRNA for a dominant trait in a large family with multiple osteochondromas. Journal of Orthopaedic Research, V28(11), P1522-1530, [Abstract] [Full Text] [PDF] DOI 10.1002/jor.21162, (IF= 2.976, (2010))
65.Ju Cui, Zai Wang, Qianni Cheng, Raozhou Lin, Xin-Mei Zhang, Po Sing Leung, Neal G. Copeland, Nancy A. Jenkins, Kwok-Ming Yao, and Jian-Dong Huang (January 2011, published ahead of print September 24, 2010) Targeted Inactivation of Kinesin-1 in Pancreatic β-Cells in vivo Leads to Insulin Secretory Deficiency. Diabetes V60(1), P320-330, [Abstract] [Full Text] [PDF] doi:10.2337/db09-1078, (IF= 8.889, (2010))
66.Zai Wang, Jian-Dong Huang*, Kin-Ling Wong, Pei-Gang Wang, Hao-Jie Zhang, Julian A. Tanner, Ottavia Spiga, Andrea Bernini, Bo-Jian Zheng, Neri Niccolai * (January 2011, Article first published online: November 16, 2010, Epub 2010 Dec 6). On the mechanisms of bananin activity against SARS coronavirus. FEBS Journal V278, P383-389, (* co-corresponding author), [Abstract] [Full Text] [PDF] doi: 10.1111/j.1742-4658.2010.07961.x, (IF= 3.790, (2011))
67.Jia-Hong Lu, Mustafa Taleb Ardah, Siva Sundara Kumar Durairajan, Liang-Feng Liu, Li-Xia Xie, Wang-Fun David Fong, Mohamed Y. Hasan, Jian-Dong Huang, Omar M. A. El-Agnaf, and Min Li (March 7, 2011, Article first published online: January 26, 2011). Baicalein Inhibits Formation of a-Synuclein Oligomers within Living Cells and Prevents Ab Peptide Fibrillation and Oligomerisation. ChemBioChem V12, P615–624, [Abstract] [Full Text] [PDF] doi: 10.1002/cbic.201000604 (IF= 3.945, (2010))
68.Siva Sundara Kumar Durairajan, Liang-Feng Liu, Jia-Hong Lu, Irene Koo, Kei Maruyama, Sookja K. Chung, Jian-Dong Huang* and Min Li* (2011 Mar 14. Epub ahead of print). Stimulation of Non-amyloidogenic Processing of Amyloid Precursor Protein by Cryptotanshinone Involves Activation and Translocation of ADAM-10 and PKC-alpha. Journal of Alzheimer's Disease V25, P245-262, (* co-corresponding author), [Abstract] [Full Text] [PDF] DOI 10.3233/JAD-2011-102085, (IF= 4.261, (2010))
69.Wen-yang Chen, John W.S. Ho, Jian-Dong Huang, Rory M. Watt. (April 18, 2011) Functional characterization of an alkaline exonuclease and single strand annealing protein from the SXT genetic element of Vibrio cholerae. BMC Molecular Biology V12(1): 16, [Abstract] [Full Text] [PDF], doi:10.1186/1471-2199-12-16 (IF= 3.188, (2010))
70.Bin Yu, Mei Yang, Ho Yin Bosco Wong, Rory M. Watt, Erwei Song, Bo-Jian Zheng, Kwok-yung Yuen, Jian-Dong Huang (July 2011, Epub ahead of print May 25, 2011) A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy. Applied Microbiology and Biotechnology V91(1), P177-188. [Abstract] [Full Text] [PDF], DOI 10.1007/s00253-011-3317-0 (IF= 3.425, (2011))
71.Muhan Chen, Jian-Dong Huang, Hong Kui Deng, Suisui Dong, Wen Deng, Sze Lan Tsang, Michael S. Y. Huen, Leilei Chen, Tong Zan, Gui-Xia Zhu, Xin-Yuan Guan (May 26, 2011) Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability. BMC Cancer V11:199, [Abstract] [Full Text] [PDF], doi:10.1186/1471-2407-11-199 (IF= 3.745, (2011))
72.Ye Jin and Jian-Dong Huang (October 1, 2011, First published online: July 29, 2011) Engineering a portable riboswitch-LacP hybrid device for two-way gene regulation. Nucleic Acids Research V39(19):e131 doi: 10.1093/nar/gkr609, (IF= 8.026, (2011))
73.Song Lu, Lin-Yu Lu, Qiu-Ju Yuan, Mai-Har Sham, Xin-Yuan Guan, Jian-Dong Huang (January, 2012, Epub ahead of print, August 10, 2011) Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood. Neurobiology of Disease V45, P219–233, doi:10.1016/j.nbd.2011.08.006 (IF= 5.403, (2011))
74.Wen Yang, Wen-yang Chen, Hui Wang, John W. S. Ho, Jian-Dong Huang, Patrick C. Y. Woo, Susanna K.P. Lau, Kwok-Yung Yuen, Qionglin Zhang, Weihong Zhou, Mark Bartlam, Rory M. Watt, and Zihe Rao, (December, 2012, Epub ahead of print, September 5, 2011) Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis. Nucleic Acids Research V39(22), P9803-19 doi: 10.1093/nar/gkr660 (IF= 8.026, (2011)) (Awarded with the 2012 Research Output Prize (Faculty of Dentistry, the University of Hong Kong))
75.Mei Yang, Jingqi Chen, Fang Su, Bin Yu, Ling Lin, Yujie Liu, Jian-Dong Huang* and Erwei Song* (September 22, 2011 Epub ahead of print) Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Molecular Cancer V10(1):117 (*co-corresponding author) doi:10.1186/1476-4598-10-117 (IF= 3.993, (2011))
76.Tim Hon Man Chan, Leilei Chen, Ming Liu, Liang Hu, Bo-jian Zheng, Vincent Kwok-Man Poon, Yun-Fei Yuan, Jian-dong Huang, Jie Yang, George Sai-wah Tsao, Xin-Yuan Guan, (February 2012, Epub ahead of print on September 27, 2011) Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development. Hepatology V55(2):491-505 doi: 10.1002/hep.24709 (IF= 11.665, (2011))
77.Chenli Liu, Xiongfei Fu, Lizhong Liu, Xiaojing Ren, Carlos K.L. Chau, Sihong Li, Lu Xiang, Hualing Zeng, Guanhua Chen, Lei-Han Tang, Peter Lenz, Xiaodong Cui, Wei Huang*, Terence Hwa*, Jian-Dong Huang* (October 14, 2011) Sequential establishment of stripe patterns in an expanding cell population. Science V334(6053), P238-241. (*co-corresponding author) DOI: 10.1126/science.1209042 (IF= 31.377, (2010))
(Faculty of 1000 evaluations, dissents and comments for [Liu C et al. Sequential establishment of stripe patterns in an expanding cell population. Science.2011 Oct 14; 334(6053):238-41; doi: 10.1126/science.1209042]. Faculty of 1000, 12 Mar 2012. F1000.com/13985959)
78.Qiuju Yuan, Huanxing Su, Jiasong Guo, Kwok Yeung Tsang, Kathryn S.E. Cheah, Kin Chiu, Jian Yang, Wai-Man Wong, Kwok-Fai So, Jian-Dong Huang, Wutian Wu, Zhi-xiu Lin, (April, 2012, Available online 22 February 2012) Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush. Experimental Gerontology V47(4), P329-36 (IF= 3.804, (2010))
79.Siva Sundara Kumar Durairajan, Liang-Feng Liu, Jia-Hong Lu, Lei-Lei Chen, Qiuju Yuan, Sookja K. Chung, Ling Huang, Xing-Shu Li, Jian-Dong Huang* and Min Li*, (December 2012, Available online 26 March 2012) Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model. Neurobiology of Aging V33(12), P2903-19 (*co-corresponding author). DOI: 10.1016/j.neurobiolaging.2012.02.016 (IF= 6.634, (2010))
80.Xiongfei Fu, Lei-Han Tang, Chenli Liu, Jian-Dong Huang, Terence Hwa, and Peter Lenz (May 8, 2012) Stripe formation in bacterial systems with density-suppressed motility. Physical Review Letters. V108, 198102 (IF= 7.622, (2010))
81.Bin Yu*, Mei Yang*, Lei Shi, Yandan Yao, Qinqin Jiang, Xuefei Li, Lei-Han Tang, Bo-Jian Zheng, Kwok-yung Yuen, David K. Smith, Erwei Song#, Jian-Dong Huang# (Epub June 1, 2012) Explicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain. Scientific Reports V2:436 (*Equal contribution; # co-corresponding author) DOI: 10.1038/srep00436.
82.Mei Y. Choi, Ying Wang, Leo L.Y. Wong, Wen-yang Chen, Jian-Dong Huang, Julian A. Tanner and Rory M. Watt (August 3, 2012) The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities. PLoS ONE V7(8): e42561. doi:10.1371/journal.pone.0042561 (IF= 4.092, (2011))
83.Hao Wu, Hao-Jie Zhang, Xiao-min Zhang, Hui-fang Xu, Ming Wang, Jian-Dong Huang, Bo-Jian Zheng (September 12, 2012) Identification of Drug Resistant Mutations in HIV-1 CRF07_BC Variants Selected by Nevirapine In Vitro. PLoS ONE V7(9): e44333. doi:10.1371/journal.pone.0044333 (IF= 4.092, (2011))
84.Songyue Zheng#, Bin Yu#, Min Chen, Ke Zhang, Yan-Hong Hua, Rory M. Watt, Bo-Jian Zheng*, Kwok-Yung Yuen*, Jian-Dong Huang* (Published: September 26, 2012) Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines. BMC Immunology V13(54) (#Equal contribution; *co-corresponding author). (Highly accessed) doi:10.1186/1471-2172-13-54 (IF= 2.531, (2011))
85.Qiuju Yuan, Huanxing Su, Wing Hin Chau, Cheung Toa Ng, Jian-Dong Huang, Wutian Wu, Zhi-xiu Lin, (2013, Epub 2013 Jan 11) Behavioral Stress Fails to Accelerate the Onset and Progression of Plaque Pathology in the Brain of a Mouse Model of Alzheimer’s Disease. PLoS One V8(1):e53480 (IF= 4.092, (2011)) doi: 10.1371/journal.pone.0053480.
86.Zai Wang, Ju Cui, Jing Wang, Xin-Mei Zhang, Wai Man Wong, Neal G. Copeland, Nancy A. Jenkins, Julian A. Tanner, Kathryn S E Cheah, Wu-Tian Wu* and Jian-Dong Huang* (February 1, 2013) Kinesin-1 controls the localization of myofibrils components for their assembly and linkage to the myotendinous junctions. Development V140(3), P617-626 (* co-corresponding author), doi:10.1242/dev.085969. (IF= 6.596, (2011))
87.Zai Wang, Wenqian Xue, Xiuling Li, Raozhou Lin, Ju Cui, and Jian-Dong Huang (2013, Available online 9 February 2013) Dissect Kif5b in nuclear positioning during myogenesis: the KLC binding domain and the autoinhibitory peptide are both indispensable. Biochemical and Biophysical Research Communications V432: P242–247. (IF= 2.484, (2011)) http://dx.doi.org/10.1016/j.bbrc.2013.02.006
88.Qiuju Yuan, Huanxing Su, Yalun Zhang, Wing Hin Chau, Cheung Toa Ng, You-Qiang Song, Jian-Dong Huang, Wutian Wu and Zhi-Xiu Lin, (2013) Amyloid pathology in spinal cord of the transgenic Alzheimer’s disease mice is correlated to the corticospinal tract pathway. Journal of Alzheimer's Disease (accepted). (IF=3.745, (2011))
89.Siva Sundara Kumar Durairajan, Liang-Feng Liu, Jia-Hong Lu, Lei-Lei Chen, Qiuju Yuan, Sookja K. Chung, Ling Huang, Xing-Shu Li, Jian-Dong Huang* and Min Li*, (December 2012, Available online 26 March 2012) “Berberine amelioratesβ-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model”, Neurobiology of Aging V33(12), P2903-19 (*co-corresponding author). DOI: 10.1016/j.neurobiolaging.2012.02.016 (IF= 6.634, (2010))
90.Xiongfei Fu, Lei-Han Tang, Chenli Liu, Jian-Dong Huang, Terence Hwa, and Peter Lenz (May 8, 2012) “Stripe formation in bacterial systems with density-suppressed motility”, Physical Review Letters. V108, 198102 (IF= 7.943, (2012))
91.Bin Yu*, Mei Yang*, Lei Shi, Yandan Yao, Qinqin Jiang, Xuefei Li, Lei-Han Tang, Bo-Jian Zheng, Kwok-yung Yuen, David K. Smith, Erwei Song#, Jian-Dong Huang# (Epub June 1, 2012) “Explicit hypoxia targeting with tumor suppression by creating an “obligate”anaerobic Salmonella Typhimurium strain”, Scientific Reports V2:436 (*Equal contribution; # co-corresponding author) DOI: 10.1038/srep00436. (IF= 2.927, (2012))
92.Mei Y. Choi, Ying Wang, Leo L.Y. Wong, Wen-yang Chen, Jian-Dong Huang, Julian A. Tanner and Rory M. Watt (August 3, 2012) “The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities”, PLoS ONE V7(8): e42561. doi:10.1371/journal.pone.0042561 (IF= 4.092, (2011))
93.Hao Wu, Hao-Jie Zhang, Xiao-min Zhang, Hui-fang Xu, Ming Wang, Jian-Dong Huang, Bo-Jian Zheng (September 12, 2012) “Identification of Drug Resistant Mutations in HIV-1 CRF07_BC Variants Selected by Nevirapine In Vitro”, PLoS ONE V7(9): e44333. doi:10.1371/journal.pone.0044333 (IF= 4.092, (2011))
94.Songyue Zheng#, Bin Yu#, Min Chen, Ke Zhang, Yan-Hong Hua, Rory M. Watt, Bo-Jian Zheng*, Kwok-Yung Yuen*, Jian-Dong Huang* (Published: September 26, 2012) “Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines”, BMC Immunology V13(54) (#Equal contribution; *co-corresponding author). (Highly accessed) doi:10.1186/1471-2172-13-54 (IF= 2.531, (2011))
95.Qiuju Yuan, Huanxing Su, Wing Hin Chau, Cheung Toa Ng, Jian-Dong Huang, Wutian Wu, Zhi-xiu Lin, (2013, Epub 2013 Jan 11) “Behavioral Stress Fails to Accelerate the Onset and Progression of Plaque Pathology in the Brain of a Mouse Model of Alzheimer’s Disease”, PLoS One V8(1):e53480 (IF= 4.092, (2011)) doi: 10.1371/journal.pone.0053480.
96.Zai Wang, Ju Cui, Jing Wang, Xin-Mei Zhang, Wai Man Wong, Neal G. Copeland, Nancy A. Jenkins, Julian A. Tanner, Kathryn S E Cheah, Wu-Tian Wu* and Jian-Dong Huang* (February 1, 2013) “Kinesin-1 controls the localization of myofibrils components for their assembly and linkage to the myotendinous junctions”, Development V140(3), P617-626 (*co-corresponding author), doi:10.1242/dev.085969. (IF= 6.596, (2011))
97.Zai Wang, Wenqian Xue, Xiuling Li, Raozhou Lin, Ju Cui, and Jian-Dong Huang (2013, Available online 9 February 2013) “Dissect Kif5b in nuclear positioning during myogenesis: the KLC binding domain and the autoinhibitory peptide are both indispensable”, Biochemical and Biophysical Research Communications V432: P242–247. (IF= 2.484, (2011)) http://dx.doi.org/10.1016/j.bbrc.2013.02.006
98.Qiuju Yuan, Huanxing Su, Yalun Zhang, Wing Hin Chau, Cheung Toa Ng, You-Qiang Song, Jian-Dong Huang, Wutian Wu and Zhi-Xiu Lin, (2013 Mar 11. Epub ahead of print) “Amyloid pathology in spinal cord of the transgenic Alzheimer’s disease mice is correlated to the corticospinal tract pathway”, Journal of Alzheimer's Disease V35(4): P 675-685. doi: 10.3233/JAD-122323 (IF=3.745, (2011))
99.Shuhai Lin, Hongde Liu, Basem Kanawati, Liangfeng Liu, Jiyang Dong, Min Li, Jiandong Huang, Philippe Schmitt-Kopplin and Zongwei Cai (June 2013, Epub March 14, 2013) “Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer’s disease in CRND8 mice”, Analytical and Bioanalytical Chemistry V405(15): P5105-5117. (IF= 3.778, (2011)) DOI 10.1007/s00216-013-6825-1
100.Zai Wang, Wenqian Xue, Raozhou Lin, Xiuling Li, Ju Cui, and Jian-Dong Huang (2013, published on June 15, 2013)“N-terminus of desmin controls its retrograde transportation in differentiating myoblast cells (结蛋白N端结构域决定其在分化的肌母细胞中的负向运输)”, Journal of China-Japan Friendship Hospital (中日友好医院学报), V27(3): P164-167
101.Ye Jin *, Jianting Wu, Yannan Li, Zhiming Cai and Jian-Dong Huang * (2013 published on September 1, 2013, Epub ahead of print July 9, 2013) “Modification of the RpoS network with an artificial small RNA”, Nucleic Acids Research, V41(17):8332-8340. (*co-corresponding author) (IF=8.278, (2012))
102.Shuhai Lin, Basem Kanawati, Liangfeng Liu, Michael Witting, Min Li, Jiandong Huang, Philippe Schmitt-Kopplin, Zongwei Cai (January 15, 2014) “Ultrahigh resolution mass spectrometry-based metabolic characterization reveals cerebellum as a disturbed region in two animal models”, Talanta V118: P45–53. (IF= 3.498, (2012))
103.Siva Sundara Kumar Durairajan, Pui-Yee Yuen, Lei-Lei Chen, Ka-Yan Kwok, Liang-Feng Liu, Ju-xian Song, Quan-Bin Han, Lei Xue, Sookja K.Chung, Jian-Dong Huang and Min Li (2014) “Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models”, PLoS ONE V9(3): e92954. doi:10.1371/journal.pone.0092954 (IF= 4.092, (2011))
104.Baozhong Zhang*, YanHong Hua*, Bin Yu*, Candy ChoiYi Lau, JianPiao Cai, SongYue Zheng, WingCheong Yam, Richard Yi-Tsun Kao, Konghung Sze, Bo-Jian Zheng, Kwok-Yung Yuen** and Jian-Dong Huang** (January 2015. Epub ahead of print 2014 Nov 3.) “Recombinant ESAT-6-like proteins provoke protective immune responses against invasive Staphylococcus aureus disease in a murine model”, Infection and Immunity V83(1):339-345. doi: 10.1128/IAI.02498-14, (* Equal contribution; ** Corresponding authors) (IF= 4.156, (2013))
105.Ho-Chuen Leung, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Han-Jun Zhao,, Chung-Yan, Cheung, Fai Ng, Jian-Dong Huang, Bo-Jian Zheng (2015, published online April 8, 2015) “An H5N1 based matrix protein 2 ectodomain tetrameric peptide vaccine 2 provided cross-protection against lethal infection of H7N9 influenza virus”, Emerging Microbes & Infections V4, e22; doi:10.1038/emi.2015.22. (IF= 5.776 (2019))
106.Ju Cui *☯, Xiuling Li☯, Zhigang Duan☯, Wenqian Xue, Zai Wang, Song Lu, Raozhou Lin, Mengfei Liu, Guixia, Zhu, Jian-Dong Huang * (2015, published April 17, 2015) “Analysis of Kif5b expression during mouse kidney development”, PLOS One V10(4):e0126002. doi: 10.1371/journal.pone.0126002. eCollection 2015 (*Corresponding authors,☯These authors contributed equally to this work.) (IF= 3.534, (2013))
107.Ju Cui*, Guoxiang Jin, Bin Yu, Zai Wang, Raozhou Lin, Jian-Dong Huang * (July 17-24, 2015, published online: May 20, 2015) “Stable knockdown of Kif5b in MDCK cells leads to epithelial-mesenchymal transition”, Biochemical and Biophysical Research Communications. V463(1-2), P 123-129. (*Corresponding authors) doi: 10.1016/j.bbrc.2015.05.045 (IF= 2.281, (2013))
108.Jian-Dong Huang, Bojian Zheng, and Kwok-Yung Yuen (June, 2015) “Live recombinant Salmonella oral vaccine against avian influenza viruses”, Hong Kong Medical Journal, V21(3) Supplement 4, Page 14-16
109.Zhu-Ling Guo, Bin Yu, Bo-Tao Ning, Shing Chan, Qiu-Bin Lin, James Chun-Bong Li, Jian-Dong Huang *, Godfrey Chi-Fung Chan * (Published online: August 19, 2015), “Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma”, Journal of Hematology & Oncology V8:99, (* co-corresponding author) DOI 10.1186/s13045-015-0196-3) (IF= 4.812, (2014))
110.Lei Shi, Bin Yu, Chunhui Cai, Wei Huang, Bo-Jian Zheng, David K. Smith, Kwok-Yung Yuen, Jian-Dong Huang (Jan., 2016, published online: December 10, 2015) “Combined prokaryotic-eukaryotic delivery and expression of therapeutic factors through a primed autocatalytic positive-feedback loop”, Journal of Controlled Release V222 pp. 130 – 140 doi:10.1016/j.jconrel.2015.12.005 (IF= 7.705, (2014))
111.Zhi Tang, Liangfeng Liu, Yongle Li, Jiyang Dong, Min Li, Jian-Dong Huang, Shuhai Lin and Zongwei Cai (2016, Epub ahead of print: 2016 January 28) “Urinary Metabolomics Reveals Alterations of Aromatic Amino Acid Metabolism of Alzheimer’s Disease in the Transgenic CRND8 Mice”, Current Alzheimer Research V13(6) pp. 1-13 DOI: 10.2174/1567205013666160129095340 (IF= 3.889, (2014))
112.Mengjie Wang, Qi Dong, Hua Wang, Yaqing He, Ying Chen, Hong Zhang, Rong Wu, Xinchun Chen, Boping Zhou, Hsiang-fu Kung, Canhua Huang, Yuquan Wei, Jian-Dong Huang, Hongxi Xu, Ming-Liang He (February 01, 2016) “Oblongifolin M, an active compound isolated from a Chinese Medical herb Garcinia oblongifolia, potently inhibits Enterovirus 71 reproduction through downregulation of ERp57”, Oncotarget. V7(8) pp8797-8808 DOI: 10.18632/oncotarget.7122 (IF= 6.359, (2014))
113.Ju Cui, Guoxiang Jin, Ting Lei, Zai Wang, Jian-Dong Huang*, Jianping Cai* (May 2016)“Knockdown of Kif5b Confers Stem Cell Properties to MDCK Cells沉默Kif5b赋予MDCK细胞干性”, Journal of Medical Research医学研究杂志V45(5), P 58-62. (*Corresponding authors) doi:10.11969/j.issn.1673-548X.2016.05.014
114.Ju Cui*, Jing Pang, Ya-Jun Lin, Ping Jiang, Huan Gong, Zai Wang, Jian Li, Jian-Ping Cai, Jian-Dong Huang*, Tie-Mei Zhang* (August 5, 2016; Epub 2016 Jun 3) “Conventional kinesin KIF5B mediates adiponectin secretion in 3T3-L1 adipocytes”, Biochemical and Biophysical Research Communications. V476(4), P 620-626. (*Corresponding authors) doi: 10.1016/j.bbrc.2016.06.008 (IF= 2.281, (2013))
115.Lei Shi, Bin Yu, Chunhui Cai, and Jian-Dong Huang (2016, published online: 24 August 2016) “Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice”, AMB Express V6(56) pp. 1 – 10 DOI 10.1186/s13568-016-0226-8 (IF= 2.167, (2015))
116.Isabelle Munoz, Luca Danelli, Julien Claver, Nicolas Goudin, Mathieu Kurowska, Iris Karina Madera-Salcedo, Jian-Dong Huang, Alain Fischer, Claudia Gonzalez-Espinosa, Geneviève de Saint Basile, Ulrich Blank and Gaël Ménasché (Oct. 24, 2016) “Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex”, The Journal of Cell Biology V 215(2) pp. 203-216 (IF= 8.717, (2015) DOI: 10.1083/jcb.201605073
117.Baozhong Zhang, Jianpiao Cai, Bin Yu, Yanhong Hua, Candy Choiyi Lau, Richard Yi Tsun Kao, Kong-Hung Sze, Kwok-Yung Yuen*, and Jian-Dong Huang* (2016, published online October 22, 2016) “A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile”, BMC Infectious Diseases V16(596) (* co-corresponding author) (IF= 2.690, (2015)) DOI: 10.1186/s12879-016-1924-1; URL: http://www.biomedcentral.com/1471-2334/16/596
118.Qi Zhang, Jinming Cui, Hailin Meng, Bingzhao Zhang, Ting Wei, Jian-Dong Huang, Chenli Liu (November, 2016)“Synthesis of Seven Milk Proteins in Escherichia Coli”,集成技术Journal of Integration Technology V5(6), p79-84 (IF= 0.477, (2017))
119.JD Huang, BJ Zheng, KY Yuen (2016). “A bioshield against influenza virus infection by commensal bacteria secreting antiviral peptide”, Hong Kong Medical Journal, V22(Suppl 4): S13-5
120.Chang-Xian Li*, Bin Yu*, Lei Shi, Wei Geng PhD, Qiu-Bin Lin, Chang-Chun Ling, Mei Yang, Kevin T.P. Ng, Jian-Dong Huang** and Kwan Man** (2017, Published online on: November 30, 2016) “An “obligate” anaerobic Salmonella strain YB1 suppresses liver tumor growth and metastasis in nude mice”, Oncology Letters V13: 177-183, (* Equal contribution; ** Corresponding authors) DOI: 10.3892/ol.2016.5453 (IF= 0.987, (2013))
121.Lizhong Liu, Wei Huang, and Jian-Dong Huang (19 January 2017, featured article) “Synthetic circuits that process multiple light and chemical signal inputs”, BMC Systems Biology V11(1): p5-14 DOI 10.1186/s12918-016-0384-y (IF= 2.208, (2015))
122.Sicong He*, Wenqian Xue*, Zhigang Duan, Qiqi Sun, Xuesong Li, Huiyan Gan, Jiandong Huang** and Jianan Y. Qu,** (2017, Received 27 Dec 2016; revised 17 Feb 2017; accepted 17 Feb 2017; published 23 Feb 2017) “Multimodal Nonlinear Optical Microscopy Reveals Critical Role of Kinesin-1 in Cartilage Development”, Biomedical Optics Express V8(3), p1771-1782, (* Equal contribution; ** Corresponding authors) (IF=3.344, (2015))
123.Shicheng Su, Jianyou Liao, Jiang Liu, Di Huang, Chonghua He, Fei Chen, LinBing Yang, Wei Wu, Jianing Chen, Ling Lin, Yunjie Zeng, Nengtai Ouyang, Xiuying Cui, Herui Yao, Fengxi Su, Jian-Dong Huang, Qiang Liu, Judy Lieberman, Erwei Song (March 14, 2017) “Blocking the Recruitment of Naïve CD4+ T Cells Reverses Immunosuppression in Breast Cancer”, Cell Research. V27(4): p461-482. (IF= 14.812, (2015)) doi: 10.1038/cr.2017.34
124.Nga Chu LUI, Wing Yip TAM1, Caiji GAO, Jian-dong Huang, Chi Chiu WANG, Liwen JIANG, Wing Ho YUNG and Kin Ming KWAN (Published 18 May 2017) “Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin”, Nature Communications V8, p15079 (IF= 11.329, (2015)) DOI: 10.1038/ncomms15079
125.Ju Cui, Jing Pang, Ya-Jun Lin, Huan Gong, Zhen-He Wang, Yun-Xuan Li, Jin Li, Zai Wang, Ping Jiang, Da-Peng Dai, Jian Li, Jian-Ping Cai, Jian-Dong Huang*, Tie-Mei Zhang* (2017, published online February 27, 2017) “Adipose-specific Deletion of Kif5b Exacerbates Obesity and Insulin Resistance in a Mouse Model of Diet-induced Obesity”, FASEB Journal. V31(6): p2533-2547. (*Corresponding authors) (IF= 5.299, (2015)) doi:10.1096/fj.201601103R
126.Siva Sundara Kumar Durairajan, Venkat R. Chirasani, Sravan Gopalakrishnan Shetty, Ashok Iyaswamy, Sandeep Malampati, Juxian Song, Liangfeng Liu, Jian-Dong Huang, Sanjib Senapatib, Min Li (April 17, 2017) “Salvianolic acid B decreases the generation of amyloid-β by modulating BACE-1 activity”, Current Alzheimer Research (published online) (IF= 3.145, (2015)) doi: 10.2174/1567205014666170417103003
127.Yanxiang Ni, Bo Cao, Tszshan Ma, Gang Niu, Yingdong Huo, Jiandong Huang, Danni Chen, Yi Liu, Bin Yu, Michael Q Zhang, and Hanben Niu (Published May 9, 2017) “Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probes”, eLife V6:e21660 DOI: http://dx.doi.org/10.7554/eLife.21660 (IF= 8.282, (2015))
128.Bo-Tao Ning, Bin Yu, Shing Chan, Jian-liang Chan, Jian-Dong Huang *, Godfrey Chi-Fung Chan * (Published: June 3, 2017), “Treatment of Neuroblastoma with an Engineered “Obligate” Anaerobic Salmonella typhimurium Strain YB1”, Journal of Cancer 8(9):1609-1618. doi: 10.7150/jca.18776. eCollection 2017, (* co-corresponding author)) (IF= 2.916, (2016))
129.Baozhong Zhang, JianPiao Cai, Bin Yu, Lifeng Xiong, Qiubin Lin, SongYue Zheng, Richard Yi-Tsun Kao, Konghung SZE, Kwok-Yung Yuen*, and Jian-Dong Huang* (July 15, 2017, Published online June 13, 2017) “Immunotherapy Targeting Adenosine Synthase A Decreases Severity of Staphylococcus aureus Infection in Mouse Model”, Journal of Infectious Diseases V216, p245-253 (* co-corresponding author) [Abstract] (IF= 6.344, (2015)) DOI: 10.1093/infdis/jix290
130.Siva Sundara Kumar Durairajan, Ashok Iyaswamy, Sravan Gopalakrishnan Shetty, Ananth Kumar Kammella, Sandeep Malampati, Wenbin Shang, Chuanbin Yang, Juxian Song, Sookja Chung, Jian-Dong Huang, Kaliappan Ilango, Quan-Bin Han and Min Li (Published online:24 July 2017) “A modified formulation of Huanglian-Jie-Du Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer’s disease”, Scientific Reports V7:6238 (IF= 3.057, (2015)) doi:10.1038/s41598-017-06217-9
131.Jia Li, Zhuo Mao, Jian-Dong Huang, Jun Xia (March 1, 2018, Epub January 3, 2018) “PICK1 is Essential for Insulin Production and the Maintenance of Glucose Homeostasis”, Molecular Biology of the Cell V29(5):pp587-596. doi: 10.1091/mbc.E17-03-0204.. (IF= 3.685, (2016))
132.Chen Xu, Baozhong Zhang, Qiubin Lin, Jian Deng, Bin Yu, Smriti Arya, Kwok-yung Yuen, and Jian-Dong Huang (25 April 2018) “Live attenuated Salmonella typhimurium Vaccines delivering SaEsxA and SaEsxB via Type III Secretion System Confer Protection against Staphylococcus aureus Infection”, BMC Infectious Diseases, 18:195. https://doi.org/10.1186/s12879-018-3104-y
133.Frédéric Adam, Alexandre Kauskot, Mathieu Kurowska, Nicolas Goudin, Isabelle Munoz, Jean-Claude Bordet, Jian-Dong Huang, Alain Fischer, Delphine Borgel, Geneviève de Saint Basile, Olivier D. Christophe, Gaël Ménasché (published March 8, 2018) “Kinesin-1 regulates platelet secretion and thrombus stability through the interaction with the granular Slp4/Rab27b effector complex”, Arteriosclerosis, Thrombosis, and Vascular Biology V38:1037-1051 (IF= 6.01, (2015)) DOI: https://doi.org/10.1161/ATVBAHA.117.310373
134.Lei Shi, Xiaolong Tang, Minxian Qian, Zuojun Liu, Fanbiao Meng, Li Fu, Zimei Wang, Wei-Guo Zhu, Jian-Dong Huang, Zhongjun Zhou and Baohua Liu (July 23, 2018) “A SIRT1-centered circuitry regulates breast cancer stemness and metastasis”, Oncogene V37, pp6299–6315 (IF= 6.854, (2017)) DOI: https://doi.org/10.1038/s41388-018-0370-5
135.Ling Liu, Zhi-Min Zong, Qian Liuc, Shuang-Shuang Jiang, Qian Zhang, Lan-Qi Cen, Jian Gao, Xiao-Ge Gao, Jian-Dong Huang, Yi Liu, Hong Yao (published 01 September 2018) “A novel galactose-PEG-conjugated biodegradable copolymer is an efficient gene delivery vector for immunotherapy of hepatocellular carcinoma”, Biomaterials V184 p20–30 (IF= 8.806, (2017)) DOI: https://doi.org/10.1016/j.biomaterials.2018.08.064
136.Luo YS, Zhuo Y, Zhang K, Liu X, Hofer E and Huang JD (2018) “Kif5b Modulates Processing and Secretion of von Willebrand Factor in Endothelial Cells and Mice”, Cardiovascular Pharmacology: Open Access, Volume 7 • Issue 5 • 1000249. DOI: 10.4172/2329-6607.1000249.
137.Ke Zhang, Cun Li, Yusi Luo, Lei Wen, Dong Wang, Bosco Ho-Yin Wong, Xiaoyu Zhao, Man Chun Chiu, Shuofeng Yuan, Hanjun Zhao, Jie He, Michael E. Bose, Kelly J. Henrickson, Jian-Dong Huang, Bojian Zheng, Hin Chu, Jie Zhou (January 2019, Received 26 April 2018; Received in revised form 27 November 2018; Accepted 29 November 2018, Available online 29 November 2018) “Establishment of a lethal aged mouse model of human respiratory syncytial virus infection”, Antiviral Research V161, p125–133, DOI https://doi.org/10.1016/j.antiviral.2018.11.015, (IF= 4.307, (2017))
138.Yan-Xiang Ni*, Nan Zhou*, Wen-Qian Xue*, Li Rong, Wing-Ho Yung, Rao-Zhou Lin, Richard Yi-Tsun Kao, Zhi-Gang Duan, Hai-Tao Sun, Hua-Rui Gong, Xu-Ming Tang1, Wen Zhang, Shuang Qi, Sookja Chung, You-Qiang Song and Jian-Dong Huang (2018, published online December 25, 2018) “A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating”, Cell Discovery Volume 4, Article number: 65. DOI 10.1038/s41421-018-0067-5 (https://rdcu.be/bejLN) (IF= 6.255, (2019))
139.Raozhou Lin*, Zhigang Duan*, Haitao Sun*, Man-Lung Fung*, Hansen Chen, Jing Wang, Chi-Fai Lau, Di Yang, Yu Liu, Yanxiang Ni, Zai Wang, Ju Cui, Wutian Wu, Wing-Ho Yung, Ying-Shing Chan, Amy C.Y. Lo, Jun Xia, Jiangang Shen, and Jian-Dong Huang (Available online February 18, 2019, March 29, 2019) “Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity”, iScience v13, pp82-97. doi: 10.1016/j.isci.2019.02.009 (* Equal contribution) (IF= 4.447, (2019))
140.Jian Deng, Xiaolei Wang, Bao-Zhong Zhang, Peng Gao, Qiubin Lin, Richard Yi-Tsun Kao, Kwok-Yung Yuen*, and Jian-Dong Huang* (Published online September 4, 2019) “Broad and effective protection against Staphylococcus aureus is elicited by a multi-valent vaccine formulated with novel antigens”, mSphere, V4(5). pii: e00362-19, 2019 (IF= 3.575, (2019)) DOI: 10.1128/mSphere.00362-19 (co-corresponding authors)
141.Huiyan Gan, Guixia Zhu, Wenqian Xue, Danny Chan, Chuanhai Fu, Kathryn S.E. Cheah, and Jian-Dong Huang (Published: 16 October 2019) "KIF5B modulates central spindle organization in late-stage cytokinesis in chondrocytes”, Cell & Bioscience V9, Article number: 85 (IF=3.355, (2018)) DOI: https://doi.org/10.1186/s13578-019-0344-5
142.Jingnan Yang, Smriti Arya, Pingsai Lung, Qiubin Lin, Jian-Dong Huang∗, Quan Li∗(received on 28 Jun 2019, accepted on 24 Sep 2019 and first published on 17 Oct 2019)“Hybrid nanovaccine for co-delivery of mRNA antigen and adjuvant”, Nanoscale V11, pp 21782-21789: (∗Co-corresponding author) (IF=6.970, (2018)) DOI: 10.1039/C9NR05475H
143.Smriti Arya, Qiubin Lin, Nan Zhou, Xiang Gao*, Jian-Dong Huang* (Received 7 October 2019, Accepted 16 December 2019, Available online 16 January 2020) “Strong immune responses induced by direct local injections of modified mRNA-lipid nanocomplex”, Molecular Therapy-Nucleic Acids Volume 19, pp: 1098-1109. (∗Co-corresponding author) (IF= 8.886, (2020)) DOI: https://doi.org/10.1016/j.omtn.2019.12.044
144.Junjun Zhao#, Albert Hiu Ka Fok#, Ruolin Fan, Pui-Yi Kwan, Hei-Lok Chan, Louisa Hoi-Ying Lo, Ying-Shing Chan, Wing-Ho Yung, Jian-Dong Huang, Cora Sau Wan Lai and Kwok-On Lai (2020) “Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory”, eLife 2020;9:e53456. (IF= 8.140, (2020)) DOI: https://doi.org/10.7554/eLife.53456 (#Equal contribution to the study)
145.Meriem Belabed, François-Xavier Mauvais, Sophia Maschalidi, Mathieu Kurowska, Nicolas Goudin, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Peter Van Endert, Fernando E. Sepulveda and Gaël Ménasché, (Published: 14 April 2020) “Kinesin-1 is required for antigen cross-presentation by inducing the scission of tubulations from early endosomes in dendritic cells”, Nature Communications V11, Article number 1817: (IF= 14.919, (2020)) DOI: https://doi.org/10.1038/s41467-020-15692-0
146.Kemeng Zhu, Huan Chen, Jin Jin, Ning Wang, Guixing Ma, Jiandong Huang, Jiuqing Xin*, Hongming Zhang*, Henggui Liu* (Accepted for publication on 24 Mar 2020, published online 21 April 2020) “Functional identification and structural analysis of a new lipoate protein ligase in Mycoplasma hyopneumoniae”, Frontiers in Cellular and Infection Microbiology, section Molecular Bacterial Pathogenesis. V10: Article 156 (IF= 5.293, (2020)) DOI: https://doi.org/10.3389/fcimb.2020.00156
147.Anson Cho Kiu Ng†, Min Yao†, Stephen Yin Cheng, Jing Li, Jian-Dong Huang, Wutian Wu*, Gilberto Ka Kit Leung* and Haitao Sun* (05 June 2020) “Protracted morphological changes in the corticospinal tract within the spinal cord after intracerebral hemorrhage in mice”, Frontiers in Neuroscience, section Neurodegeneration Volume 14 | Article 506. https://doi.org/10.3389/fnins.2020.00506 (IF= 4.677, (2020)) († Equal contribution)
148.Bao-zhong Zhang, Ye-fan Hu, Lin-lei Chen, Thomas Yau, Yi-gang Tong, Jing-chu Hu, Jian-piao Cai, Kwok-Hung Chan, Ying Dou, Jian Deng, Xiao-lei Wang, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To*, Kwok-yung Yuen*, and Jian-Dong Huang* (Published online: July 1, 2020) “Mining of Epitopes on Spike Protein of SARS-CoV-2 from COVID-19 Patients”, Cell Research Volume 30 Number 8 Page 702-704 https://doi.org/10.1038/s41422-020-0366-x (* co-corresponding author) (IF= 25.617, (2020))
149.Xuming Tang, Tingting Cao, Yun Zhu, Liyi Zhang, Jinna Chen, Tengfei Liu, Xiaoyan Ming, Shuo Fang, Yun-fei Yuan, Lingxi Jiang*, Jian-Dong Huang*, Xin-Yuan Guan* (Published: 02 July 2020) "PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway”, Cell Death & Disease, V11:510 (* co-corresponding author) (IF= 8.469, (2020)) https://doi.org/10.1038/s41419-020-2700-0
150.Bao-zhong Zhang$, Hin Chu$*, Shuo Han$, Huiping Shuai$, Jian Deng, Ye-fan Hu, Hua-rui Gong, Andrew Chak-Yiu Lee, Zijiao Zou, Thomas Yau, Wutian Wu, Ivan Fan-Ngai Hung, Jasper Fuk-Woo Chan, Kwok-Yung Yuen*, Jian-Dong Huang* (Published online: 04 August 2020) “SARS-CoV-2 productively infects human brain organoids”, Cell Research V30, pages 928–931 https://doi.org/10.1038/s41422-020-0390-x ($equal contribution, *co-corresponding author) (IF= 25.617, (2020))
151.Agnese I. Curatolo∗, Nan Zhou∗, Yongfeng Zhao∗, Chenli Liu, Adrian Daerr, Julien Tailleur†and Jian-Dong Huang†(Received 28 September 2018, Accepted 04 June 2020, Published 24 August 2020)“Cooperative pattern formation in multi-species bacterial colonies”, Nature Physics (article) V16, PP 1152–1157 (∗equal contribution;†co-corresponding author) (IF= 20.034, (2020))
DOI: https://doi.org/10.1038/s41567-020-0964-z,
bioRxiv: http://biorxiv.org/cgi/content/short/798827v1,
DOI: https://doi.org/10.1101/798827:
152.Kelvin Kai-Wang To, Ivan Fan-Ngai Hung, Jonathan Daniel Ip, Allen Wing-Ho Chu, Wan-Mui Chan, Anthony Raymond Tam, Carol Ho-Yan Fong, Shuofeng Yuan, Hoi-Wah Tsoi, Anthony Chin-Ki Ng, Larry Lap-Yip Lee, Polk Wan, Eugene Tso, Wing-Kin To, Dominic Tsang, Kwok-Hung Chan, Jian-Dong Huang, Kin-Hang Kok, Vincent Chi-Chung Chen, Kwok-Yung Yuen (Published 25 August 2020) “COVID-19 re-infection by a phylogenecally distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing”, Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, ciaa1275. doi: 10.1093/cid/ciaa1275. (IF= 9.079, (2020))
153.Tingting Xiao, Axin Yan, Jian-Dong Huang, Erik M. Jorgensen, and Nagendra P. Shah (Received 12 August 2020, Accepted 7 October 2020, Accepted manuscript posted online 16 October 2020, Print 2020 Dec 17) “Comparative Peptidomic and Meta-transcriptomic Analyses Reveal Improved Gamma-amino butyric acid Production Machinery in Levilactobacillus brevis NPS-QW 145 Co-cultured with Streptococcus thermophilus ASCC1275 during Milk Fermentation”, Applied and Environmental Microbiology, v87(1):e01985-20 DOI: 10.1128/AEM.01985-20 (IF= 4.792, (2020))
154.Chaiyaporn Kuwentrai#, Jinming Yu#, Li Rong, Bao-zhong Zhang, Ye-fan Hu, Hua-rui Gong, Ying Dou, Jian Deng, Jian-Dong Huang*, Chenjie Xu* (Received: 9 September 2020; Revised: 8 October 2020; Accepted: 12 October 2020; First published: 25 November 2020) “Transdermal delivery of Receptor-Binding Domain of SARS-CoV-2 Spike protein with dissolvable microneedles to induce humoral and cellular responses in mice”, Bioengineering & Translational Medicine, e10202 (# equal contribution, * co-corresponding author) (IF= 10.711, (2020)) doi: https://doi.org/10.1002/btm2.10202
155.Bao-Zhong Zhang1, Xiaolei Wang1, Shuofeng Yuan1, Wenjun Li1, Ying Dou1, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Jian-Piao Cai, Kenn Ka-Heng Chik, Kaiming Tang, Ye-Fan Hu, Jing-Chu Hu, Smaranda Ruxandra Badea, Hua-Rui Gong, Xuansheng Lin, Hin Chu, Xuechen Li, Kelvin Kai-Wang To, Li Liu, Zhiwei Chen, Ivan Fan-Ngai Hung, Kwok Yung Yuen2, Jasper Fuk-Woo Chan2, Jian-Dong Huang2 (Received 4 February 2021; Revised 31 March 2021; Accepted 20 April 2021; Accepted author version posted online: 23 Apr 2021) “A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters”, Emerging Microbes & Infections V10:1, 874-884 (1 equal contribution, 2 co-corresponding author) (IF= 7.163, (2020)) doi: https://doi.org/10.1080/22221751.2021.1921621
156.Qiubin Lin, Li Rong, Xian Jia, Renhao Li, Bin Yu, Jingchu Hu, Xiao Luo, Badea Smaranda-ruxandra, Chen Xu, Guofeng Fu, Kejiong Lai, Ming-chun Lee, Baozhong Zhang, Huarui Gong, Nan Zhou, Xiao Lei Chen, Shu-hai Lin*, Guo Fu*, Jian-Dong Huang*, (Received: 28 January 2020; Accepted: 25 March 2021; Published online: 05 May 2021) “Salmonella potently inhibits cancer metastasis by activating IFN-γ-dependent NK cell”, Nature Communications V12:2537 (* co-corresponding author) (IF= 14.919, (2020)) DOI: https://doi.org/10.1038/s41467-021-22755-3
157.Chaiyaporn Kuwentrai#, Jinming Yu#, Ying Dou, Bao-zhong Zhang, Ye-fan Hu, Hua-rui Gong, Jian-Dong Huang*, Chenjie Xu* (Received 26 Jan 2021; Accepted 04 May 2021; Published 18 May 2021) “Induction of humoral and cellular immunity by dissolvable microneedle delivery of SARS-CoV-2 Nucleocapsid protein”, Journal of Immunology Research Volume 2021 |Article ID 5531220 (# equal contribution, * co-corresponding author) (IF= 4.818, (2020)) DOI: https://doi.org/10.1155/2021/5531220
158.Dongying Xie#, Hin Chu#, Qiutao Ding#, Dong YANG#, Gefei Huang, Zongwei Cai*, Jiandong Huang*, and Zhongying Zhao* (2021) “A stark difference in the profiles of defective viral transcripts between SARS-CoV-2 and SARS-CoV”, Journal of Infection (Accepted: June 18, 2021, Available online July 1, 2021) (# equal contribution, * co-corresponding author) (IF= 6.072, (2020)) DOI: https://doi.org/10.1016/j.jinf.2021.06.020
159.Jian Deng*, Bao-zhong Zhang*, Hin Chu*, Xiao-lei Wang, Yixin Wang, Hua-Rui Gong, Renhao Li, Dong Yang, Cun Li, Ying Dou, Peng Gao, Jian-piao Cai, Meilin Jin, Qian Du, Jasper Fuk-Woo Chan, Richard Yi-Tsun Kao, Kwok-Yung Yuen, and Jian-Dong Huang# (Received 14 March 2021, Revised 13 July 2021, Accepted 13 July 2021, Available online 28 July 2021) “Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening T cell responses”, EBioMedicine, Volume 70, 103505. (*Equal contribution, #co-corresponding author) DOI: https://doi.org/10.1016/j.ebiom.2021.103505 (IF= 8.143, (2020))
160.Shuxin Yang, Wenjuan Zhao, Muchun Zhu, Huijuan Hu, Weijie Wang, Zhongsheng Zang, Meiling Jin, Jiandong Huang, Chenli Liu, Xuefei Li, Peng Yin and Nan Li (Submitted on: 21 May 2021; published on 19 August 2021) “Tumor temporal proteome profiling reveals the immunological triple offensive induced by synthetic anti-cancer Salmonella”, Frontiers in Immunology, section Cancer Immunity and Immunotherapy Volume 12:712936| (IF= 7.561, (2020)) DOI: https://doi.org/10.3389/fimmu.2021.712936
161.Ya-Nan Tan, Yong-Peng Li, Jian-Dong Huang, Min Luo, Shan-Shan Li, Anne Wing-Mui Lee, Fu-Qiang Hu, Xin-Yuan Guan, (Received 12 May 2021, Revised 6 September 2021, Accepted 21 September 2021, Available online 24 September 2021, 1 December 2021) “Thermal-sensitive lipid nanoparticles potentiate anti-PD therapy through enhancing drug penetration and T lymphocytes infiltration in metastatic tumor”, Cancer Letters Volume 522, Pages 238-254, DOI: https://doi.org/10.1016/j.canlet.2021.09.031 (IF=8.679, (2020))
162.Bao-Zhong Zhang*†, Danyu Hu†, Ying Dou†, Xiaolei Wang, Jingchu Hu, Shao-Zhen Xing, Wenjun Li, Jian-piao Cai, Meilin Jin, Qiubin Lin, Min Li, Kwok-Yung Yuen, Jian-Dong Huang* (Received: 24 June 2021; Accepted: 20 September 2021; Published: 20 October 2021) “Identification and Evaluation of Recombinant Outer Membrane Proteins as vaccine candidates against Klebsiella pneumoniae”, Frontiers in Immunology, section Vaccines and Molecular Therapeutics, Volume 12 | Article 730116, († equal contribution, * co-corresponding author) DOI: https://doi.org/10.3389/fimmu.2021.730116, (IF= 7.561, (2020))
163.Huiping Shuai†, Jasper Fuk-Woo Chan†,*, Terrence Tsz-Tai Yuen†, Chaemin Yoon, Jing-Chu Hu, Lei Wen, Bingjie Hu, Dong Yang, Yixin Wang, Yuxin Hou, Xiner Huang, Yue Chai, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Rui-Qi Zhang, Wan-Mui Chan, Jonathan Daniel Ip, Allen Wing-Ho Chu, Ye-Fan Hu, Jian-Piao Cai, Kwok-Hung Chan, Jie Zhou, Siddharth Sridhar, Bao-Zhong Zhang, Shuofeng Yuan, Anna Jinxia Zhang, Jian-Dong Huang, Kelvin Kai-Wang To, Kwok-Yung Yuen*, Hin Chu*, (Received 14 July 2021, Revised 7 October 2021, Accepted 7 October 2021, Available online 21 October 2021) “Emerging SARS-CoV-2 variants expand species tropism to murines”, EBioMedicine Volume 73, November 2021, 103643, († equal contribution, * co-corresponding author) DOI: https://doi.org/10.1016/j.ebiom.2021.103643 (IF= 8.143, (2020))
164.Jingjing Sun and Jian-Dong Huang (2021) “Outer membrane protein C as a presenting platform targeting the antigen to outer membrane vesicle”, CHINESE JOURNAL OF BIOLOGICALS (accepted)
孙京京,黄建东(2021)“外膜蛋白C作为蛋白呈递平台将抗原定位至细菌外膜囊泡的可行性”,中国生物制品学杂志
165.Huiping Shuai, Jasper Fuk-Woo Chan1, Bingjie Hu1, Yue Chai1, Terrence Tsz-Tai Yuen1, Feifei Yin2,3,4, Xiner Huang, Chaemin Yoon, Jing-Chu Hu, Huan Liu, Jialu Shi, Yuanchen Liu, Tianrenzheng Zhu, Jinjin Zhang, Yuxin Hou, Yixin Wang, Lu Lu, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Melinda A. Brindley, Bao-Zhong Zhang, Jian-Dong Huang, Kelvin Kai-Wang To, Kwok-Yung Yuen#, Hin Chu#, (Received, 23 December 2021; Accepted, 19 January 2022; Published, 21 January 2022) “Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron”, Nature (#co-corresponding author) DOI: https://doi.org/10.1038/s41586-022-04442-5 (IF= 49.962, (2020))
166.Ya-Nan Tan, Jian-Dong Huang, Yong-Peng Li, Shan-Shan Li, Min Luo, Jie Luo, Anne Wing-Mui Lee, Li Fu, Fu-Qiang Hu, Xin-Yuan Guan, (First published: 08 December 2021) “Near-Infrared Responsive Membrane Nanovesicles Amplify Homologous Targeting Delivery of Anti-PD Immunotherapy against Metastatic Tumors”, Advanced Healthcare Materials, e2101496, DOI: https://10.1002/adhm.202101496 (IF= 9.933, (2020))
167.Ye-fan Hu†, Jing-chu Hu†, Hin Chu, Thomas Yau, Bao-zhong Zhang*, Jian-Dong Huang*, (Received: 18 December 2021 / Revised: 9 February 2022 / Accepted: 12 February 2022 / Published: 14 February 2022) “In-silico analysis of monoclonal antibodies against SARS-CoV-2 Omicron”, Viruses, V14(2), 390, (†equal contribution, *co-corresponding author) DOI: https://doi.org/10.3390/v14020390 (IF= 5.048, (2020))
168.Hua-Rui Gong, Jing-Chu Hu, Huan Chen, Li Rong, Qiubin Lin, Bao-Zhong Zhang, Nan Li, Jian-Dong Huang, (Received on 11th Jan 2022; Peer Reviewed on 24th Jan 2022; Revised on 15th February 2022; Published on 27th February 2022) “Inhibition of breast cancer cell migration by serum obtained from engineered Salmonella-treated mouse”, British Journal of Bio-Medical Research, Vol.06, Issue 01, Pg.1871 - 1881, January - February 2021, DOI: https://doi.org/10.24942/bjbmr.2022.913
169.Ye-fan Hu†, Jing-chu Hu†, Hua-rui Gong†, Antoine Danchin, Ren Sun, Hin Chu, Ivan Fan-Ngai Hung, Kwok Yung Yuen, Kelvin Kai-Wang To, Bao-zhong Zhang*, Thomas Yau*, Jian-Dong Huang*, (Received: 24 January 2022; Accepted: 25 February 2022; Published: 24 March 2022) “Computation of Antigenicity Predicts SARS-CoV-2 Vaccine Breakthrough Variants”, Frontiers in Immunology, section Viral Immunology, V13, Article 861050 (†equal contribution, *co-corresponding author) DOI: https://doi.org/10.3389/fimmu.2022.861050 (IF= 8.786, (2021))
170.Bao-Zhong Zhang†, Huiping Shuai†, Hua-Rui Gong†, Jing-Chu Hu†, Bingpeng Yan†, Terrence Tsz-Tai Yuen, Ye-Fan Hu, Chaemin Yoon, Xiao-Lei Wang, Yuxin Hou, Xuansheng Lin, Xiner Huang, Renhao Li, Yee Man Au-Yeung, Bingjie Hu, Yue Chai, Ming Yue, Jian-Piao Cai, Guang Sheng Ling, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan*, Jian-Dong Huang*, Hin Chu*, (Submitted: December 8, 2021, Accepted: April 20, 2022, Published: June 8, 2022) “Bacillus Calmette–Guérin-Induced Trained Immunity Protects Against SARS-CoV-2 Infection in K18-hACE2 Mice”, JCI insight, V7(11):e157393. (†equal contribution, *co-corresponding author), DOI: https://doi.org/10.1172/jci.insight.157393 (IF= 9.533, (2021))
171.Cyril Longé, Manuela Bratti, Mathieu Kurowska, Shamila Vibhushan, Pierre David, Jian-Dong Huang, Alain Fischer, Geneviève de Saint Basile, Fernando E. Sepulveda, Ulrich Blank, Gaël Ménasché, (Received Date: 20 December 2021, Revised Date: 15 March 2022, Accepted Date: 8 April 2022, Published online: 22 April 2022) “Rab44 regulates mast cell-driven anaphylaxis by controlling kinesin-1-dependent secretory granule translocation”, Journal of Allergy and Clinical Immunology, Volume 150, Issue 3, Pages 676 – 689, S0091-6749(22)00544-9 (IF= 14.290, (2021)) DOI: https://doi.org/10.1016/j.jaci.2022.04.009
172.Jinming Yu #, Chaiyaporn Kuwentrai #, Hua-Rui Gong, Renhao Li, Bao-zhong Zhang, Xuansheng Lin, Xiaolei Wang, Jian-Dong Huang*, Chenjie Xu* (Received 4 February 2022, Revised 30 May 2022, Accepted 7 June 2022, Available online 11 June 2022) “Intradermal delivery of mRNA using cryomicroneedles”, Acta Biomaterialia, (# equal contribution, * co-corresponding author) S1742-7061(22)00353-1 (IF= 10.633, (2021)), doi: https://doi.org/10.1016/j.actbio.2022.06.015
173.Jasper Fuk-Woo Chan; Bingjie Hu; Yue Chai; Huiping Shuai; Huan Liu; Jialu Shi; Yuanchen Liu; Chaemin Yoon; Jinjin Zhang; Jing-Chu Hu; Yuxin Hou; Xiner Huang; Terrence Tsz-Tai Yuen; Tianrenzheng Zhu; Wenjun Li; Jian-Piao Cai; Cuiting Luo; Cyril Chik-Yan Yip; Anna Jinxia Zhang; Jie Zhou; Shuofeng Yuan; Bao-Zhong Zhang; Jian-Dong Huang; Kelvin Kai-Wang To; Kwok-Yung Yuen; Hin Chu (Received 29 March 2022, Revised 27 July 2022, Accepted 23 August 2022, Available online 29 August 2022, Version of Record 20 September 2022. Published: August 29, 2022) “Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2”, Cell Reports Medicine, Volume 3, Issue 9, 100743 (IF= 16.988, (2021)) doi: https://doi.org/10.1016/j.xcrm.2022.100743
174.Kunza Latif, Shagufta Naz*, Imran Altaf, Jian-Dong Huang, Rasheeda Bashir, Farheen Aslam, Shaozhen Xing (Received: 18 May 2021 | Accepted: 18 April 2022 | Published: 23 September 2022) “Optimization of Factors for Efficient Expression and Purification of spao and lamb Gene of Salmonella Enteric Subsp. S. Typhi”, Bioscience Journal (*corresponding author) V38, e38084. https://doi.org/10.14393/BJ-v38n0a2022-61149 (IF= 0.347, (2020))
175.Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang* and Siva Sundara Kumar Durairajan* (RECEIVED 22 September 2022, ACCEPTED 10 October 2022, PUBLISHED 25 October 2022) “Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models” Frontiers in Molecular Biosciences, (*corresponding author) (IF= 4.615, (2021)) doi: https://doi.org/10.1016/j.jinf.2022.12.016
176.Hua-Rui Gong†, Ye-fan Hu†, Xuechen Li, Hin Chu, Thomas Yau, Bao-Zhong Zhang*, Jian-Dong Huang* (Received 27 September 2022, Published online10 November 2022) “Non-Neutralizing Epitopes Shade Neutralizing Epitopes against Omicron in a Multiple Epitope-Based Vaccine”, ACS Infectious Diseases, († equal contribution, * co-corresponding author) V8 (12), 2586-2593 (IF= 5.084, (2021)) doi: https://doi.org/10.1021/acsinfecdis.2c00488
177.Lixiang Zhai +, Chunhua Huang +, Ziwan Ning +, Yijing Zhang +, Min Zhuang, Wei Yang, Xiaolei Wang, Jingjing Wang, Eric Lu Zhang, Haitao Xiao, Ling Zhao, Yan Y. Lam, Chi Fung Willis Chow, Jiandong Huang, Shuofeng Yuan, Kui Ming Chan, Chun-Su Yuan, Johnson Yiu-Nam Lau, Hoi Leong Xavier Wong *, Zhao-xiang Bian * (Received 13 March 2022, Revised 6 September 2022, Accepted 15 November 2022, Available online 9 December 2022) “Pathogenetic Role of Gut Microbiota Shunting of Dietary Phenylalanine to Phenethylamine in Diarrhea-Predominant Irritable Bowel Syndrome”, Cell Host & Microbe, (+ Co-first authors, * co-corresponding author) (accepted) (IF= 31.316, (2022)) doi: https://doi.org/10.1016/j.chom.2022.11.006
178.Meiling Jin†, Jingchu Hu†, Lili Tong, Bao-zhong Zhang, Jian-Dong Huang (Received: October 18, 2022, Revised: December 6, 2022, Published online: December 12, 2022) “The epitope basis of embryonic stem cell-induced antitumor immunity against bladder cancer”, Advanced Healthcare Materials, e2202691, (†equal contribution) (IF= 11.092, (2021)) doi: https://doi.org/10.1002/adhm.202202691
179.Xue Li, Kuan Peng, Franco WT Cheng, David CL Lam, Ching Lung Cheung, Celine SL Chui, Francisco TT Lai, Eric YF Wan, Carlos KH Wong, Tiantian Ma, Samson HH Yum, Esther WY Chan, Jian Dong Huang, Chak Sing Lau, Mary SM Ip, Ian CK Wong (Accepted 14 December 2022, Available online 17 December 2022) “Tuberculosis following two-dose SARS-CoV-2 vaccination with messenger RNA vaccine (BNT162b2) and inactivated virus vaccine (CoronaVac)”, Journal of Infection, (accepted) (IF=38.637, (2021)) doi: https://doi.org/10.1016/j.jinf.2022.12.016
180.Xuanming Guo, Jianli Cao, Jian-Piao Cai, Jiayan Wu, Jiangang Huang, Pallavi Asthana, Sheung Kin Wong, Zi-Wei Ye, Susma Gurung, Yijing Zhang, Sheng Wang, Zening Wang, Xin Ge, Hiu Yee Kwan, Aiping Lu, Kui ming Chan, Nathalie Wong, Jiandong Huang, Zhongjun Zhou, Zhao-xiang Bian, Shuofeng Yuan, and Hoi Leong Xavier Wong (Received: 6 May 2022; Accepted: 12 December 2022; Published online: 23 December 2022) “Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2”, Nature Communications, V 13, Article number: 7907 (IF= 17.7, (2021)) doi: https://doi.org/10.1038/s41467-022-35590-x
181.Jingjing Sun†, Xuansheng Lin†, Yige He, Baozhong Zhang, Nan Zhou*, Jian-dong Huang* (RECEIVED 05 November 2022, ACCEPTED 06 January 2023, PUBLISHED 19 January 2023) “A bacterial outer membrane vesicle-based click vaccine elicits potent immune response against Staphylococcus aureus in mice”, Frontiers in Immunology (section Vaccines and Molecular Therapeutics), Volume 14:1088501. (†equal contribution, *co-corresponding) (IF= 8.787, (2021)) https://doi.org/10.3389/fimmu.2023.1088501
综述性论文如下:
1.Jian-Dong Huang, Lin Leng, and Xian-shu Wang (December, 1987).“Cell Surface DNA”Progress in Biochemistry and Biophysics生物化學與生物物理進展. V6: 23-25. (IF= 0.215, (2005))
2.Albert J. Courey and Jian-Dong Huang (March, 1995). “The Establishment and Interpretation of Transcription Factor Gradients in the Drosophila Embryo”, Biochimica Et Biophysica Acta-Gene Structure And Expression. V1261 N1: 1-18. (IF= 2.506, (2005))
3.Hsiang-fu Kung and Jian-Dong Huang (February, 2001). “The mouse model and human disease”, Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao中國醫學科學院學報), V23 (1): 2-7 [Abstract]
4.Hsiang-fu Kung and Jian-Dong Huang (March, 2001). “The mouse model and human disease (Sequel)”, Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao中國醫學科學院學報), V23 (2): 97-102
5.Hsiang-fu Kung and Jian-Dong Huang (April, 2001). “The mouse model and human disease (Sequel): Cancer”, Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao中國醫學科學院學報), V23 (3): 205-209
6.Jian-Dong Huang (February 2008) “The Huang Laboratory”, BioTechniques, V44(2): 173
7.Sui Cheung Man, Siva Sundara Kumar Durairajan, Wan Fung Kum, Jia Hong Lu, Jian-Dong Huang, Ching Fung Cheng, Vincent Chung, Min Xu and Min Li (June 2008) “Systematic Review of the Efficacy and Safety of Herbal Medicines for Alzheimer's Disease”, Journal of Alzheimer's Disease V14(2): 209-223
8.Chenli Liu, Xiongfei Fu, Jian-Dong Huang, (December 2013) “Synthetic biology: a new approach to study biological pattern formation”, Quantitative Biology V1(4): 246–252
[Abstract] [PDF] DOI 10.1007/s40484-013-0021-3
9.WANG XiaoLei, LIU ChenLi, FU XiongFei & HUANG JianDong, (October 2015) “合成生物学:一种研究生物图案形成的新方法(Synthetic Biology: a New Means of Biological Pattern Formation Study)”,中国科学:生命科学2015年 第45卷 第10期SCIENTIA SINICA Vitae V45(10): 928 ~ 934 DOI doi: 10.1360/N052015-00151
10.Taku A. Tokuyasu, Jian-Dong Huang, (January 18, 2018) “A primer on recent developments in cancer immunotherapy, with a focus on neoantigen vaccines”, Journal of Cancer Metastasis and Treatment V4(2). DOI: 10.20517/2394-4722.2017.52
11.
12.Yunfeng Zhang张云丰, Dan He何丹, Huan Lu卢欢, Jiandong Huang黄建东*, Xiaozhou Luo罗小舟*, (Received Aug 14, 2020; Accepted Sep 22, 2020; Published Sep 23, 2020)“代谢工程改造酿酒酵母底盘细胞的研究进展(The recent research of metabolic engineering Saccharomyces cerevisiae chassis)”,科学通报doi: 10.1360/TB-2020-0494 (*Corresponding authors)
13.Xi Zhang张曦,Pengcheng Li李鹏程, Jiandong Huang黄建东*, Xiaozhou Luo戴卓君*, (Accepted 2020)“合成生物学在活体功能材料构建上的应用(Application of Synthetic Biology in Living Functional Materials)”,科学通报doi: https://doi.org/10.1360/TB-2020-0475 (*Corresponding authors)
14.王蕾†,黄建东 †,杨舒心,黄术强*,李楠* (收稿时间2020年06月17日;接受时间2020年07月27日;发布时间2020年07月28日)“定量工程生物学的化学蛋白质组学支撑性技术”,科学通报, 66卷, 3期: 356-366(2021), doi: https://doi.org/10.1360/TB-2020-0457 († 同等贡献, *联系人)
Lei Wang†, Jiandong Huang†, Shuxin Yang, Shuqiang Huang*, Nan Li*, (Received Jun 17, 2020; Accepted Jul 27, 2020; Published Jul 28, 2020) (Chemical proteomics techniques and their perspective enabling roles in quantitative engineering biology)”, Chinese Science Bulletin, Volume 66, Issue 3: 356-366, doi: https://doi.org/10.1360/TB-2020-0457 († Equally contributed to this work, *Corresponding authors)
15.Mo-Xian Chen陈沫先, Zhong Wei韦中, LiangTian田亮, Yang Tan谭扬, Jiandong Huang黄建东*, Lei Dai戴磊*, (Accepted 2020)“合成微生物群落的构建与应用(Design and application of synthetic microbial communities)”,科学通报doi: https://doi.org/10.1360/TB-2020-0487; (*Corresponding authors)
16.白艳芬,聂朋,熊成鹤,温骏林, Jiandong Huang黄建东*,梅辉*, (Accepted 2020)“以非天然核酸为遗传物质的人工生命构建(Construction of synthetic life forms with genetic materials comprising unnatural nucleic acids)”,科学通报doi: https://doi.org/10.1360/TB-2020-0474
17.ZHOU Nan, XIA Yingting, HUANG JianDong, (2020)“合成生物学在探索生物图案形成基本原理中的应用与展望(Applications and Prospects of Synthetic Biology in Exploring the Basic Principles of Biological Pattern Formation)”,合成生物学Vol. 1, Issue (4): 470-480. doi: 10.12211/2096-8280.2020-011
18.Jinming Yu#, Chaiyaporn Kuwentrai#, Jian-Dong Huang*, Chenjie Xu*, (Submitted: 08 October 2020. Accepted: 16 December 2020. Published Online: 04 January 2021) “Carbon-based nanomaterials for viral infection management”, Biomicrofluidics, Vol.15, Issue1,011501 (#Equal contribution; *Corresponding authors) DOI: https://doi.org/10.1063/5.0032427
19.Md. Motiar Rahman*, Nan Zhou, Jian-Dong Huang (received: 20 January 2021, accepted: 23 February 2021, published: 11 March 2021) “An overview on the development of mRNA-based vaccines and their formulation strategies for improved antigen expression in vivo”, Vaccines, V9(3), P244. DOI: https://doi.org/10.3390/vaccines9030244 (*Corresponding author) (IF= 4.086, (2019))
20.Da Huo, Hua Yang, Jian-Dong Huang, Jian-Ping Cai, Ju Cui, (Received December 11, 2020; Accepted April 2, 2021; Published online on: May 5, 2021) “Roles of kinesin superfamily proteins in colorectal cancer carcinogenesis”, Oncology Reports V46: 121, DOI: https://doi.org/10.3892/or.2021.8072 (IF= 3.417, (2019))
21.黄建东(2021)“序言:合成生物学前沿研究及转化应用”,《集成技术》, 10(4): 1-2, (Jian-Dong Huang, Preface: frontier research and translational applications of synthetic biology. Journal of Integration Technology, 10(4): 1-2) DOI: 10.12146/j.issn.2095-3135.20210601001
22.黄建东*,黄琨(2021)“基因工程纳米颗粒在EB病毒疫苗研发中的应用概述”,《集成技术》, 10(4): 67-77,(*通讯作者)
Jian-Dong Huang* and Kun Huang, Recent progress in bio-engineered nanoparticles for Epstein–Barr virus vaccines, Journal of Integration Technology, 10(4): 67-77 (* corresponding author) DOI: 10.12146/j.issn.2095-3135.20210427003
23.黄建东*,韦孟溪,周楠(2021)“细菌治疗肿瘤的研究进展”,《集成技术》, 10(4): 93-101. (*通讯作者)
Jian-Dong Huang *, Mengxi Wei, Nan Zhou “Research Progress in Bacterial Tumor Therapy”, Journal of Integration Technology, 10(4): 93-101, (* corresponding author) doi: 10.12146/j.issn.2095-3135.20210427004
24.辛颖*,徐宝琪*,王军杰*,张荣荣*,温慧,王金娟,梁帆 ,金帆,黄建东#,黄术强# (2021)“用于高分辨率成像的肺器官芯片构建及肺炎模型应用研究”《集成技术》,10(4): 126-136,(#通讯作者)
XIN Ying*,XU Baoqi*,WANG Junjie *,ZHANG Rongrong*,WEN Hui,WANG Jinjuan,LIANG Fan,JIN Fan,Jian-Dong Huang #,HUANG Shuqiang,# Construction of lung-on-a-chip for high-resolution imaging and application of pneumonia model,Journal of Integration Technology, 10(4): 126-136) (# corresponding author) DOI: 10.12146/j.issn.2095-3135.20210427007
25.霍达,刘晶晶,范国庆,曾律滔,刘媛媛,蔡剑平,黄建东,崔菊(2021)“马达蛋白KIF5B基因的重组慢病毒过表达和RNA干扰载体的构建及稳定过表达和干扰结直肠癌细胞模型的建立《集成技术》(HUO Da, Liu Jingjing2, FAN Guoqing, ZENG Lvtao, LIU Yuanyuan, CAI Jianping, CUI Ju, HUANG Jiandong, Construction of KIF5B gene recombinant lentivirus overexpression and RNA interference vector and establishment of stable colorectal cancer cell models)”,专刊doi: https://doi.org/
26.Sai Krishna Guguloth, Lakshmi A R, Radhika Rajendran, Kaushik Rajaram, Thirunavukkarasu Chinnasamy, Jian-Dong Huang, Hongjie Zhang, Sanjib Senapati, Siva Sundara Kumar Durairajan (Online ahead of print 2021 Oct 5). “A Mechanistic Review on Plant-derived Natural Inhibitors of Human Coronaviruses with Emphasis on SARS-COV-1 and SARS-COV-2”, Current Drug Targets doi: 10.2174/1389450122666211005115313 (IF= 3.465, (2004))
27.Jiawen Chen, Ting Li, Jianhao Liang, Qiqi Huang, Jian-Dong Huang, Yiquan Ke and Haitao Sun (Received: October 30, 2021; Revised: November 15, 2021; Accepted: November 16, 2021, January 2022) “Current status of intratumour microbiome in cancer and engineered exogenous microbiota as a promising therapeutic strategy”, Biomedicine & Pharmacotherapy, Volume 145, 112443 (IF= 6.529, (2020)) DOI: https://doi.org/10.1016/j.biopha.2021.112443
28.Udhaya Bharathy Saravanan, Mayurikaa Namachivayam, Rajesh Jeewon, Jian-Dong Huang, Siva Sundara Kumar Durairajan (Received: June 24, 2021 Peer-review started: June 24, 2021 First decision: July 31, 2021 Revised: August 22, 2021 Accepted: November 24, 2021 Article in press: November 24, 2021 Published online: January 25, 2022) “Animal models for SARS-CoV-2 and SARS-CoV-1 pathogenesis, transmission and therapeutic evaluation”, World Journal of Virology, V11(1): 40-56 (IF= 5.15, (2020)) DOI: 10.5501/wjv.v11.i1.40
29.Looniva Shrestha*, Haiming Fan, Huiren Tao, Jian-Dong Huang (Received: 30 December 2021; Accepted: 14 February 2022; Published: 25 February 2022) “Recent strategies to combat biofilms: From antimicrobial agents to therapeutic approaches”, Pathogens, V11, 292 (* corresponding author) (IF= 3.492, (2020)) DOI: https://doi.org/10.3390/pathogens11030292 (Academic Editors: Gianfranco Donelli and Lawrence S. Young)
30.Antoine Danchin* & Jian-Dong Huang (Received: 12 July 2022, Accepted: 16 July 2022, First published: 31 August 2022) “SynBio 2.0, a new era for synthetic life: Neglected essential functions for resilience”, Environmental Microbiology (CRYSTAL BALL section), 1–15 (* corresponding author) (IF= 5.476, (2021)) DOI: http://doi.org/10.1111/1462-2920.16140
31.Meiling Jin & Jian-Dong Huang* (2022) “New mechanism to promote long-term T cell immunity by telomere transfer from antigen-presenting cells”, Cellular & Molecular Immunology (Research Highlight), (Received 31 October 2022; Accepted 01 November 2022; Published18 November 2022) (* corresponding author) (IF= 22.096, (2022)) DOI: https://doi.org/10.1038/s41423-022-00949-z
32.Jiawen Chen, Ting Li, Chun Ye, Jiasheng Zhong, Jian-Dong Huang, Hongwei Zhou, Yiquan Ke *, Haitao Sun * (Received: 3 December 2022, Revised: 17 January 2023, Accepted: 18 January 2023, Published: 21 January 2023) “The Lung Microbiome: A New Frontier for Lung and Brain Disease”, International Journal of Molecular Sciences (ijms) (*co-corresponding author) V24, 2170, DOI: https://doi.org/10.3390/ijms24032170 (IF= 6.208, (2021))
已获得及申请中的知识产权:
1.HOST CELLS DEFICIENT FOR MISMATCH REPAIR AND THEIR USE IN METHODS FOR INDUCING HOMOLOGOUS RECOMBINATION USING SINGLE-STRANDED NUCLEIC ACIDS.
Filed on May 7, 2004 as US Application # 10/841,125
United States Patent Application 20050079618
Application Number: PCT/US03/14657
2.METHOD FOR CONSTRUCTING AND MODIFYING LARGE DNA MOLECULES
Application No. 60/490,025 filed on July 24 2003
PCT Patent Application No. PCT/CN2004/000858
United States Patent Application 20050084970
U.S. Non-Provisional Application No. 10/892,579 filed on July 16, 2004.
Issued Patent No.: US 7,781,190 B2
Date of Patent: August 24, 2010
Inventors: Jian-Dong Huang, Xin-Mei Zhang, Julian Alexander Tanner
3.SYNTHETIC PEPTIDE TARGETING CRITICAL SITES ON THE SARS-ASSOCIATED CORONAVIRUS SPIKE PROTEIN RESPONSIBLE FOR VIRAL INFECTION AND A METHOD OF USE THEREOF
O/R IP00170 U.S. Provisional Patent No. 60/630,334
Inventors: Zheng BJ, Guan Y, Huang JD, He ML
4.HOST CELLS DEFICIENT FOR MISMATCH REPAIR
Publication date: 2004-12-09
Inventor(s): COURT DONALD L [US]; LI XIN-TIAN [CN]; HUANG JIAN-DONG [CN]; COSTANTINO NINA [US]; LIU DEPEI [CN]
Applicant(s): US GOVERNMENT [US]; UNIV HONG KONG [CN]; CHINESE ACAD MED SCIENCE [CN]; COURT DONALD L [US]; LI XIN-TIAN [CN]; HUANG JIAN-DONG [CN]; COSTANTINO NINA [US]; LIU DEPEI [CN]
Classification:
- international: C12N1/19; C12N1/21; C12N15/10; C12N1/19; C12N1/21; C12N15/10; (IPC1-7): C12N15/00; C12N1/19; C12N1/20; C12N1/21; C12N5/10
- European: C12N15/10B; C12R1/19
Application number: WO2003US14657 20030509
Priority number(s): WO2003US14657 20030509
5.一种有效提高基因定点转换(突变/修复)的新方法
Publication date: 2009-8-5, Publication number: CN 100523202C,
Patent No.: ZL 200310118223.X
Inventor(s):刘德培,吴雪松,辛立,殷文璇,黄建东,谢赏恩,梁植权
6.TWO-WAY, PORTABLE RIBOSWITCH MEDIATED GENE EXPRESSION CONTROL DEVICE
U.S. Non-Provisional Application No. 61/503,453 filed on June 30, 2011.
U.S. Application No. 13/534,774 filed on June 27, 2012
U.S. Patent No. 9,222,093 B2
Date of Patent: Dec. 29, 2015
Chinese Patent: Patent Number: ZL201280032539.4; Date of patent: 4 July 2017
Inventor(s): Jian-Dong Huang and Ye Jin
7.Modified Bacteria and their Uses thereof for the Treatment of Cancer
U.S. Provisional Application No. 61/687,975 filed on May 4, 2012.
U.S. Non-Provisional Patent Application filed on 26 April 2013, Application No. 13/871,716
Patent No.: US 9,127,284 B2,
Date of Patent: Sept. 8, 2015
Date of Patent: Apr. 27, 2021
Inventor(s): Jian-Dong Huang, Bin Yu, Mei Yang, and Lei Shi
8.Therapeutic Delivery and Expression System, Methods and Uses Thereof
U.S. Provisional Application No. 14/019,058 filed on September 5, 2013.
U.S. Application No. 14/019,058 filed on September 5, 2013
International application No. PCT/CN2014/000282, filed on March 17, 2014
Inventor(s): Jian-Dong Huang, Bin Yu, and Lei Shi
9.IMMUNOTHERAPEUTIC TARGETS AGAINST STAPHYLOCOCCUS AUREUS
U.S. Provisional Application No. 62/093,752 filed on December 18, 2014.
PCT Application
Application number: PCT/CN2015/097726
Application date: 17 December 2015
Inventor(s): Jian-Dong Huang, Kwok-Yung Yuen, Zhang Baozhong
10.专利号: PCT/CN2014/075210;专利名称:一种细胞培养与实验装置;专利类别:国际PCT;申请日: 4/11/2014;发明人:崔金明,曾诗杰,Olaf Eichstädt,黄建东,杜如虚
11.专利号: 201410112722.6;专利名称:一种细胞培养与实验装置;专利类别:国家发明;申请日: 3/25/2014;授权公告日:9/9/2015;发明人:崔金明,曾诗杰,艾澈熙,黄建东,杜如虚;专利权人:广州中国科学院先进技术研究所
12.专利号: 201410005155.4;专利名称:一种多功能微型生物细胞培养装置;专利类别:国家发明;申请日: 1/2/2014;授权公告日:4/29/2015;发明人:曾诗杰,崔金明,艾澈熙,陈贤帅,黄建东,杜如虚;专利权人:广州中国科学院先进技术研究所
13.专利号: 201510400517.4;专利名称:一种靶向治疗用人工驱磁细菌及其构建方法和应用;专利类别:发明专利;申请日: 2015.07.09;发明人:刘陈立,赖旺生,沈玥,黄建东;专利权人:中国科学院深圳先进技术研究院
14.专利号: 201710883356.8;专利名称:一种重组牛β-乳球蛋白及其制备方法和应用;专利类别:发明专利; 申请日:2017 .09.26;发明人:刘陈立,李小明,张齐,崔金明,蒙海林,黄建东;专利权人:广州中国科学院先进技术研究所
15.专利号:201710883353.4;专利名称:一种重组牛血清蛋白成熟肽及其制备方法和应用;专利类别:;申请日:2017.09.26;发明人:崔金明,李小明,张齐,刘陈立,蒙海林,黄建东;专利权人:广州中国科学院先进技术研究所
16.国际申请号:PCT/CN2020/073892;专利名称:Anti 2019-nCov Vaccine;专利类别:;申请日:2020年1月22日;申请人:;专利权人:香港大学深圳医院;中国科学院深圳先进技术研究院; 北京化工大学;广州医科大学附属第一医院。12个月优先权期限:2020年1月22日
17.专利号:ZL 2019 1 1232277.6;专利名称:绿脓杆菌毒素ExoS和ExoT的免疫用途及其制备方法;专利类别:发明专利;申请日:2019.12.5;发明人:黄建东,张宝中,李文君;专利权人:中国科学院深圳先进技术研究院
18.专利号:201911304124.8;专利名称:OprJ-N-M融合基因及其融合蛋白制备方法以及用途;专利类别:发明专利;申请日:2019.12.17;发明人:黄建东,张宝中,李文君;专利权人:中国科学院深圳先进技术研究院
19.一种mRNA-脂质体复合物及其应用
Chinese Patent No. ZL 2019 1 0544951.8 filed on June 21, 2019.
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专利权人:浙江智达药业有限公司
20.METHOD OF DEVELOPING A PEPTIDE-BASED VACCINE CONJUGATED WITH 1V209
U.S. Provisional Application No. 63/265,780,752 filed on December 20, 2021.
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Inventor(s): Jian-Dong Huang, Yefan Hu
21.胚胎干细胞来源的抗膀胱癌肿瘤的肿瘤抗原表位肽及其应用
Chinese Patent Application No. ZL 2021 11524107.2 filed on February 28, 2022.
Inventor(s):黄建东、金美玲、通莉莉、胡景初
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22.CANCER IMMUNOTHERAPY
U.S. Provisional Application No. 63/439,557 Filed January 17, 2023 - Dkt. 3562-PRO. A foreign filing license has been granted on February 2, 2023
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Inventor(s): Jian-Dong Huang, Renhao Li