●研究领域

研究领域围绕高性能生物医用材料展开，包括功能软物质医用材料，抗生物污染新型材料界面，以及药物可控释放技术和植介入器械等多个方面。

●个人简介

深圳理工大学医疗器械产业技术研究院医用材料与植介入中心，特聘教授，研究员，国家重大人才工程专家（青年人才）。北京科技大学材料物理与化学博士，主持参与国家级科研和市级重大技术攻关，以及企业技术攻关等项目10余项。以第一/通讯作者在Avanced Functional Materials, Biomaterials, ACS Applied Materials and Interfaces, Biomacromolecules, Acta Biomaterialia等国际重要学术期刊发表文章发表30余篇，获专利授权10余项。

●学习经历：

2006.09－2012.07 北京科技大学 材料物理与化学 博士

2011.06－2012.03 哈佛大学和麻省理工学院 访问学生

2002.09－2006.07 四川大学 材料科学·材料化学 学士

●工作经历：

2021.03－至今 国家高性能医疗器械创新中心医用材料与植介入器械中心 主任/研究员

2018.05－2021.02 CooperVision(库博光学)Advanced Development Center 化学/材料资深研发科学家

2014.07－2018.05 University of British Columbia 博士后研究员

2012.06－2014.06 北京大学 博士后研究员

●（所获荣誉）

工信部国家重大人才工程专家（青年人才）

深圳市海外高层次人才

●（科研成果）重大科技项目承担情况，代表性文章、成果转化情况

代表性科研项目：

1.工信部重大项目，骨科医疗器械及新材料（2024-至今，子任务负责人，在研）

2.国家人才项目，医疗植介入器械关键材料与部件（主持，在研）

3.工信部重大技术攻关，体外膜肺氧合机（ECMO）研制（管理/核心参与，已结题）

4.深圳市科技重大专项，骨科关节用高性能增韧氧化铝陶瓷材料关键技术研发（2025-至今，主持，在研）

5.深圳市技术攻关重点项目，新型高压超短陡脉冲房颤精准消融治疗系统关键技术研发（2022-至今，子任务负责人，在研）

6.深圳市技术攻关重点项目,治疗下肢动脉硬化闭塞症的介入器械关键技术研发（子任务负责人，已结题）

7.企业横向：高性能抗菌医用/医疗产品研发（主持，已结题）

代表性论文：

1.Z Wang,H Zhang*, AJ Chua, J Jackson, K Lin, CJ Lim, D Lange, M Chiao*, Mechanically Enhanced Nested-Network Hydrogels as a Coating Material for Biomedical Devices,Acta Biomaterialia, 2018, 70, 98-109.

2.H Zhang*, JK Jackson, M Chiao*, Microfabricated Drug Delivery Devices: Design, Fabrication and Applications,Advanced Functional Materials,2017, 27, 1703606.

3.Q Fu,H Zhang*, Z Wang, M Chiao*, Solvent-Driven Actuators Based on Soft Janus Films of Homogeneous Composition,Journal of Materials Chemistry B, 2017, 5, 4025-4030.

4.A Shademani,H Zhang*, JK Jackson, M Chiao*, Active regulation of on-demand drug delivery by magnetically triggerable microspouters,Advanced Functional Materials, 2017, 27, 1604558.

5.J Shi,H Zhang*, JK Jackson, A Shademani, M Chiao*, A robust and refillable magnetic sponge capsule for remotely triggered drug release,Journal of Materials Chemistry B, 2016, 4(46), 7415.

6.E Lee,H Zhang*, JK Jackson, CJ Lim, M Chiao*, Janus films with stretchable and waterproof properties for wound care and drug delivery applications,RSC Advances, 2016, 6 (83), 79900.

7.H Zhang, JK Jackson, C Bian, HM Burt, M Chiao*, Enzyme-Modified Hydrogel Coatings with Self-Cleaning Abilities for Low Fouling PDMS Devices,Advanced Materials Interfaces, 2015, 2, 1500154.

8.AK Gaharwar, A Patel, A Dolatshahi-Pirouz,H Zhang, K Rangarajan, G Iviglia, S-R Shin, MA Hussain, A Khademhosseini*, Elastomeric nanocomposite scaffolds made from poly (glycerol sebacate) chemically crosslinked with carbon nanotubes,Biomaterials Science, 2015, 3, 46.

9.H Zhang, M Chiao*, Anti-fouling coatings of poly-(dimethylsiloxane) devices for biological and biomedical applications,Journal of Medical and Biological Engineering, 2015, 35(2), 143.

10.H Zhang,R Hao, JK Jackson, M Chiao*, H Yu*, Janus ultrathin film from multi-level self-assembly at air–water interfaces,Chemical Communications, 2014, 94, 14843.

11.H Zhang, C Bian, JK Jackson, F Khademolhosseini, HM Burt, M Chiao*,Fabrication of robust hydrogel coatings on polydimethylsiloxane substrates using micropillar anchor structures with chemical surface modification,ACS Applied Materials & Interfaces, 2014, 6, 9126.

12.A Patel, A Gaharwar, G Iviglia,H Zhang, S Mukundan, S Mihaila, D Demarchi, A Khademhosseini*, Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers,Biomaterials, 2013, 34, 3970.

13.H Zhang, A Patel, A Gaharwar, S Mihaila, G Iviglia, S Mukundan, H Bae, H Yang*, A Khademhosseini*, Hyperbranched polyester hydrogels with controlled drug release and cell adhesion properties,Biomacromolecules, 2013, 14, 1299.

14.H Zhang, Y Dong, L Wang, G Wang*, J Wu, Y Zheng, H Yang*, S Zhu, Low swelling hyperbranched poly(amine-ester) hydrogels for pH-modulated differential release of anticancer drugs,Journal of Materials Chemistry, 2011, 21(35), 13530.

15.H Zhang, G Wang*, H Yang, Drug delivery systems for differential release in combination therapy,Expert Opinion on Drug Delivery, 2011, 8(2), 171.

16.H Zhang, C Zhao, H Cao, G Wang, L Song, G Niu, H Yang*, J Ma*, S Zhu, Hyperbranched poly(amine-ester) based hydrogels for controlled multi-drug release in combination chemotherapy,Biomaterials, 2010, 31(20), 5445.

代表性专利：

1.载药微米粒及其制备方法，ZL202210108093.4

2.组织吻合器，ZL202221667099.7

3.一种水浴环境疲劳测试装置，ZL202420465001.2