王亮，中国科学院深圳先进技术研究院副研究员，华中科技大学学士和博士，2017年加入深圳先进院医工所。主要研究方向为遗传编码荧光探针和光遗传学工具的开发及其在活细胞和活体中的成像应用。近年来以第一或通讯作者（含共同）在Nature Physics、Nature Communications、Autophagy、Journal of Physics D: Applied Physics等杂志发表论文多篇，同时以合作者身份在Neuron、PNAS等杂志上发表论文多篇，主持国家自然科学基金面上和青年项目、广东省和深圳市基础研究面上项目等，参与科技部国家重点研发计划（项目）等多项国家和省市级项目。

学习经历

2007-09至2013-06,华中科技大学,生物医学工程,博士

2003-09至2007-06,华中科技大学,生物技术,学士

科研与学术工作经历

2023-01至 今,中国科学院深圳先进技术研究院,医工所,副研究员

2017-06至2022-12,中国科学院深圳先进技术研究院,医工所,助理研究员

2014-12至2017-05, Fred Hutchinson Cancer Research Center,博士后

2013-10至2014-12, University of Texas Southwestern Medical Center,博士后

荧光探针开发和成像，信号分子的活细胞和活体检测

代表性文章

(1) Jiarui Xiong #; Liang Wang #; Jialun Lin #; Lei Ni; Rongrong Zhang; Shuai Yang; Yajia Huang; Jun Chu *; Fan Jin *; Quantifying second-messenger information transmission in bacteria, Nature Physics, 2025, 511(14)

(2) Liang Wang #; Chunling Wu #; Wanling Peng; Ziliang Zhou; Jianzhi Zeng; Xuelin Li; Yini Yang; Shuguang Yu; Ye Zou; Mian Huang; Chang Liu; Yefei Chen; Yi Li; Panpan Ti; Wenfeng Liu; Yufeng Gao; Wei Zheng; Haining Zhong; Shangbang Gao; Zhonghua Lu; Pei-Gen Ren; Ho Leung Ng; Jie He; Shoudeng Chen; Min Xu; Yulong Li; Jun Chu *; A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging, Nature Communications, 2022, 13(1): 5363

(3) Wenfeng Liu #; Chang Liu #; Pei-Gen Ren *; Jun Chu *; Liang Wang *; An improved genetically encoded fluorescent cAMP indicator for sensitive cAMP imaging and fast drug screening, Frontiers in Pharmacology, 2022, 13: 902290

(4) Wenfeng Liu #; Mengying Deng #; Chengming Yang #; Feng Liu; Xinmeng Guan; Yichen Du; Liang Wang *; Jun Chu *; Genetically encoded single circularly permuted fluorescent protein-based intensity indicators, Journal of Physics D: Applied Physics, 2020, 53: 113001

(5) Liang Wang; Jonathan A. Cooper; Optogenetic control of the Dab1 signaling pathway, Scientific Reports, 2017, 7: 43760

(6) Liang Wang; Lei Liu; Lingsong Qin; Qingming Luo; Zhihong Zhang; Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant, Science China. Life Sciences, 2017, 60(4): 333-344

(7) Liang Wang #; Min Chen #; Jie Yang; Zhihong Zhang; LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cells, Autophagy, 2013, 9(5): 756-769

(8) Jie Yang #; Liang Wang #; Fei Yang; Haiming Luo; Lingling Xu; Jinling Lu; Shaoqun Zeng; Zhihong Zhang; mBeRFP, an improved large Stokes shift red fluorescent protein, Plos One, 2013, 6(8)

#：共同第一作者；*：共同通讯作者

专利

(1)储军;王亮;胡雅婧;一种cAMP荧光探针G-Flamp3及其应用,2023-12-07,中国, CN202311674388.9

(2)储军;王亮;刘文峰;一种cAMP荧光探针G-Flamp2和G-Flamp2b及其应用和试剂盒, 2022-10-12,中国, CN202211247977.4

(3)储军;王亮;cAMP荧光探针R-Flamp2m及其应用和试剂盒, 2022-02-28,中国, CN202210187183.7

(4)储军;王亮;李玲玲;高性能红色cAMP荧光探针及其应用, 2020-12-15,中国, ZL 2020 1 1473325.3

(5)王亮;储军;一种cAMP荧光探针G-Flamp1的应用, 2020-04-29,中国, ZL 2020 1 0354936.X

(6)储军;王亮;荧光亮度宽幅变化的环磷酸腺苷荧光探针, 2019-12-09,中国, ZL 2019 1 1251920.X

(7)骆清铭;张智红;王亮;一种判定微管相关蛋白1轻链3蛋白斑点类型的方法, 2013-1-29,中国, ZL 2013 1 0031926.2

专利

(1)吴天准;徐臻;视觉假体装置、系统及其控制方法、存储介质, 2019-11-27,中国, ZL201911189756.4，入股深圳市中科先见医疗科技有限公司

(2)吴天准;徐臻;视觉假体装置和视觉假体系统, 2019-11-27,中国, ZL201922102671.X