刘赣，教研助理教授、特聘副教授、PI、博士生导师，深圳市孔雀计划高层次人才。主要从事基于生物材料的药物递送系统、干细胞工程化及组织工程研究，同时具有丰富的生物医药公司核酸递送技术和相关产品研发经验。已在Advanced Functional Materials，Biomaterials，Theranostics，Chemical Engineering Journal等国际知名期刊发表SCI收录论文近70篇，引用5000余次，H-index38。已授权10余项中国及PCT发明专利。曾主持和承担包括国自然青年基金及中国博士后面上项目一等资助等10余项国家省市级科研项目。担任《Chinese Chemical Letters》（中国化学快报）青年编委，深圳市工信局项目评审专家及多个专业委员会委员。

学习经历

2012.02-2014.02美国加州大学洛杉矶分校 化学与生物分子工程 博士联合培养

2008.09-2014.06南开大学 高分子物理与化学 博士

2004.09-2008.06南开大学 材料化学 本科

科研与学术工作经历

2026.02-至今 深圳理工大学生物医学工程学院 教研助理教授

2024.10-2026.02 南方医科大学深圳医院副研究员

2021.09-2024.10百达联康生物科技（深圳）有限公司研发总监

2020.02-2021.08中山大学药学院（深圳）副教授

2017.03-2020.02中山大学药学院（深圳）特聘研究员

2015.03-2017.03清华大学深圳研究生院 生命与健康学部 博士后

1）基于高分子的核酸药物递送系统：基于自主开发的生物可降解高分子材料，构建肝外靶向的核酸药物递送系统，用于肿瘤、自免疫性疾病和重大转染病等防治研究。

2）工程化干细胞与组织工程：基于核酸纳米粒等生物活性材料对干细胞进行工程化改造，进而实现功能增强或增加，并结合组织工程，实现组织修复和医生再生。

代表性文章

(1)Gan Liu, Wenqiang Xiang, Miaomiao Guan, Chuntao Xu, Jin Liu, Chao Zhao*, Yang Deng*, Biodegradable hyperbranched poly(amine-co-ester)-based polymeric nanoparticles for mRNA delivery, Advanced Functional Materials 2025, 2425986

(2)Yue Xiong, Chao He, Junyang Qi, Meimei Xiong, Shuna Liu, Jingxin Zhao, Yunzhen Li,Gan Liu*, Wenbin Deng*,Black Phosphorus Nanosheets Activate Tumor Immunity of Glioblastoma by Modulating the Expression of Immunosuppressive Molecules PD-L1, Biomaterials2025, 317, 123062

(3)Yue Xiong, Chao He, Xun Lin, Ke Cheng, Fumei He, Jingxin Zhao, Mengjie Yang, Hong Gao, Fangjie He, Xiaopei Zhang, Zeqi Liu,Gan Liu*, Wenbin Deng*,Black Phosphorus Nanosheets Inhibit Glioblastoma Cell Migration and Invasion through Modulation of WNT/β-catenin and NOTCH Signaling Pathways, Chemical Engineering Journal2024,481,148614

(4)Fumei He, Ke Cheng, Junyang Qi, Fangjie He, Chengjun Chu, Yue Xiong, Jingxin Zhao, JiaQi Ding, FanShu Kong, ZiMeng Cao,Gan Liu*, Wenbin Deng*,Black phosphorus nanosheets enhance differentiation of neural progenitor cells for improved treatment in spinal cord injury, Chemical Engineering Journal 2023, 472,144977

(5)FumeiHe,Zeqi Liu, Jian Xu, Yue Xiong, Xiaopei Zhang, Junyang Qi, XunLin, Chengjun Chu, Lan Shen,Gan Liu*, Wenbin Deng*,Black phosphorus nanosheets suppress oxidative damage ofstem cells for improved neurological recovery, Chemical Engineering Journal 2023, 451,138737

(6)Miaomiao Luo, Yun Zhou, Nansha Gao, Wei Cheng, Xusheng Wang, Jinxiu Cao, Xiaowei Zeng,Gan Liu*, Lin Mei*, Mesenchymal stem cells transporting black phosphorus-based biocompatible nanospheres: Active trojan horse for enhanced photothermal cancer therapy, Chemical Engineering Journal 2020, 385, 123942

(7)Gan Liu, Hsiang-I Tsai, Xiaowei Zeng, Junyang Qi, Miaomiao Luo, Xusheng Wang, Lin Mei*,Wenbin Deng*,Black phosphorus nanosheets-based stable drug delivery system via drug-self-stabilization for combined photothermal and chemo cancer therapy,Chemical Engineering Journal2019,375,121917

(8)Wei Cheng, Junpeng Nie, Nansha Gao,Gan Liu*, Wei Tao, Xiaojun Xiao, Lijuan Jiang, Zhigang Liu, Xiaowei Zeng*, Lin Mei*, A Multifunctional Nanoplatform against Multidrug Resistant Cancer: Merging the Best of Targeted Chemo/Gene/Photothermal Therapy, Advanced Functional Materials 2017, 27:1704135

(9)Gan Liu, Hsiang-i Tsai, Xiaowei Zeng, Yixiong Zuo, Wei Tao, Jun Han,Lin Mei*,Phosphorylcholine-based stealthy nanocapsules enabling tumor microenvironment-responsive doxorubicin release for tumor suppression,Theranostics2017,7(5):1192-1203

(10)Gan Liu, Hongjun Gao,Yixiong Zuo, Xiaowei Zeng, Wei Tao, Hsiang-i Tsai,Lin Mei*,DACHPt-loaded unimolecular micellesbased on hydrophilic dendritic block copolymersforenhanced therapy oflung cancer,ACS Applied Materials & Interfaces 2017, 9:112-119

专利

（1）邓扬；刘赣；向文强；韦豪；管苗苗；一种阳离子聚酯及其制备方法和应用，中国ZL202211419916.1，PCT/CN2022/131745

（2）刘赣；向文强；管苗苗；邓扬；一种高效的阳离子聚酯及其应用，PCT/CN2023/099194

（3）向文强；刘赣；管苗苗；郭冬；黄朝翔；邓扬；一种用于核酸药物的复合材料及其制备方法和应用，中国ZL202311758608.6

（4）邓文斌；刘泽琦；刘赣；和福美；齐军阳；林珣；熊月；一种水凝胶及其制备方法与应用，中国, CN202310743304.6

（5）邓文斌；刘赣；梅林；曾小伟；一种铂药/黑磷复合物及其制备方法和应用，中国ZL2018113603363.3

（6）刘赣；梅林；张逸凌；曾小伟；左一雄；黄来强；树枝状嵌段共聚物PAM-PGlu-b-TPGS及其制备方法与应用，中国ZL201610539862.0

（7）Yunfeng Lu, Yang Liu, Jing Wen,Gan Liu,Stealth Nanocapsules for Protein Delivery,PCT/WO2016/085808A1